Sodium Thiosulfate
- Generic Name
- Sodium Thiosulfate
- Indication
⑴治疗氰化物中毒，与高铁血红蛋白形成剂联合应用；
⑵治疗降压药硝普钠过量中毒；
⑶治疗可溶性钡盐（如硝酸钡）中毒；
⑷治疗砷、汞、铋、铅等金属中毒，但首选二巯基类药物及依地酸类药物；
⑸作为非特异性抗炎药，用于皮炎、湿疹、荨麻疹、药物性皮炎、副银屑病的治疗【1.《糖皮质激素类药物临床应用指导原则》；2.《中西医结合系统药物治疗湿疹皮炎类皮肤病专家共识》2015；3.《临床诊疗指南皮肤病与性病分册》】。
Sodium Thiosulfate Treatment of Vascular Calcification in ESRD
- Conditions
- Complication of HemodialysisCardiovascular Diseases
- Interventions
- First Posted Date
- 2007-12-06
- Last Posted Date
- 2012-11-20
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 48
- Registration Number
- NCT00568399
- Locations
- 🇺🇸
Washington University, Saint Louis, Missouri, United States
BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain
- Conditions
- Drug/Agent Toxicity by Tissue/OrganCognitive/Functional EffectsBrain and Central Nervous System TumorsBreast CancerPsychosocial Effects of Cancer and Its Treatment
- Interventions
- First Posted Date
- 2006-11-09
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- OHSU Knight Cancer Institute
- Registration Number
- NCT00397501
Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors
- Conditions
- Anaplastic OligoastrocytomaAnaplastic OligodendrogliomaMixed GliomaOligoastrocytoma
- Interventions
- Other: Laboratory Biomarker AnalysisOther: Quality-of-Life Assessment
- First Posted Date
- 2006-03-17
- Last Posted Date
- 2022-03-17
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 33
- Registration Number
- NCT00303849
- Locations
- 🇺🇸
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, United States
🇺🇸OHSU Knight Cancer Institute, Portland, Oregon, United States
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
- Conditions
- Central Nervous System Lymphoma
- Interventions
- Other: Quality-of-Life AssessmentBiological: Rituximab
- First Posted Date
- 2006-02-17
- Last Posted Date
- 2021-09-22
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 81
- Registration Number
- NCT00293475
- Locations
- 🇺🇸
Cleveland Clinic Foundation, Cleveland, Ohio, United States
🇺🇸Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States
🇺🇸Good Samaritan Hospital - Cincinnati, Cincinnati, Ohio, United States
Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors
- Conditions
- Bone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/OrganLong-term Effects Secondary to Cancer Therapy in Children
- First Posted Date
- 2005-10-13
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 2
- Registration Number
- NCT00238173
- Locations
- 🇺🇸
OHSU Knight Cancer Institute, Portland, Oregon, United States
Extrapleural Pneumonectomy With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Amifostine and Sodium Thiosulfate
- Conditions
- Pleural MesotheliomaMalignant Pleural Mesothelioma
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2014-03-27
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 85
- Registration Number
- NCT00165516
- Locations
- 🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Brigham and Women's Hospital, Boston, Massachusetts, United States
Pleurectomy/Decortication Followed by Intrathoracic/Intraperitoneal Heated Cisplatin for Malignant Pleural Mesothelioma
- Conditions
- Pleural MesotheliomaMalignant Pleural Mesothelioma
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2014-03-27
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 70
- Registration Number
- NCT00165555
- Locations
- 🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
🇺🇸Brigham and Women's Hospital, Boston, Massachusetts, United States
Pleurectomy/Decortication With Intraoperative Intrathoracic/Intraperitoneal Heated Cisplatin With Sodium Thiosulfate
- Conditions
- Pleural MesotheliomaMalignant Pleural Mesothelioma
- Interventions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2016-09-09
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 16
- Registration Number
- NCT00165503
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇺🇸Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Combination Chemotherapy With or Without Sodium Thiosulfate in Preventing Low Platelet Count While Treating Patients With Malignant Brain Tumors
- Conditions
- Malignant Glioma
- Interventions
- Other: Quality-of-Life Assessment
- First Posted Date
- 2004-01-12
- Last Posted Date
- 2022-05-03
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 48
- Registration Number
- NCT00075387
- Locations
- 🇺🇸
Cleveland Clinic Foundation, Cleveland, Ohio, United States
🇺🇸OHSU Knight Cancer Institute, Portland, Oregon, United States
🇺🇸University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, United States
Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen
- Conditions
- Drug/Agent Toxicity by Tissue/OrganBrain and Central Nervous System TumorsLymphomaThrombocytopenia
- Interventions
- First Posted Date
- 2003-12-11
- Last Posted Date
- 2023-07-06
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 17
- Registration Number
- NCT00074165
- Locations
- 🇺🇸
Good Samaritan Hospital Cancer Treatment Center, Hatton Institute, Cincinnati, Ohio, United States
🇺🇸Knight Cancer Institute at Oregon Health and Science University, Portland, Oregon, United States
Drug Development Updates
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