DeepMed Research

Cortisone

Generic Name: Cortisone

Drug Type: Small Molecule

Chemical Formula: C_₂₁H_₂₈O_₅

CAS Number: 53-06-5

Unique Ingredient Identifier: V27W9254FZ

Background: A naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite hydrocortisone. (From Martindale, The Extra Pharmacopoeia, 30th ed, p726)

Indication: 肾上腺皮质激素类药。主要用于肾上腺皮质功能减退症及垂体功能减退症的替代治疗，亦可用于过敏性和炎症性疾病；局部外用于治疗虹膜睫状体炎、虹膜炎、角膜炎、过敏性结膜炎等。也可用于治疗角膜移植后的排斥反应和眼科手术后的炎症反应。

Clinical Trials

Comparative, Randomized Study on the Anti-inflammatory and Regenerative Efficacy of a New Medical Device (DM) Based on Hydrolyzed Collagen Peptides in Patients With Femoro-acetabular Impingement Undergoing Hip Arthroscopy

Not Applicable

Completed

Conditions: Hip Arthroscopy
Femoroacetabular Impingement
Hip Osteoarthritis
Hydrolyzed Collagen Peptides

Interventions: Device: Class III medical Hydrolyzed Collagen Peptides PEP-52 (Peptys)
Drug: Cortisone

First Posted Date: 2023-10-13

Last Posted Date: 2024-01-30

Lead Sponsor: Istituto Ortopedico Rizzoli

Target Recruit Count: 25

Registration Number: NCT06082271

Locations: 🇮🇹
Istituto Ortopedico Rizzoli, Bologna, Italy

Congenital Adrenal Hyperplasia Once Daily Hydrocortisone Treatment

Phase 4

Conditions: Congenital Adrenal Hyperplasia

Interventions: Drug: Conventional Glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone)
Drug: Dual release hydrocortisone (plenadren)

First Posted Date: 2018-11-30

Last Posted Date: 2022-03-22

Lead Sponsor: Federico II University

Target Recruit Count: 150

Registration Number: NCT03760835

Locations: 🇮🇹
Federico II University, Naples, Italy

BMA vs Cortisone for Glenohumeral Osteoarthritis

Phase 2

Completed

Conditions: Osteo Arthritis Shoulders

Interventions: Biological: Bone Marrow Aspirate
Drug: Cortisone

First Posted Date: 2018-07-09

Last Posted Date: 2022-07-20

Lead Sponsor: Women's College Hospital

Target Recruit Count: 34

Registration Number: NCT03580148

Locations: 🇨🇦
Women's College Hospital, Toronto, Ontario, Canada

Safety and Efficacy Adipose-Derived Stem Cell Injection Partial Thickness Rotator Cuff Tears

Not Applicable

Completed

Conditions: Rotator Cuff Tear - Partial Thickness

Interventions: Biological: Adipose derived regenerative cells
Drug: Cortisone Injectable

First Posted Date: 2016-09-28

Last Posted Date: 2021-02-11

Lead Sponsor: InGeneron, Inc.

Target Recruit Count: 18

Registration Number: NCT02918136

Locations: 🇺🇸
Sanford Orthopedics and Sports Medicine - Fargo, Fargo, North Dakota, United States
🇺🇸
Sanford orthopedics and Sports Medicine - Sioux Falls, Sioux Falls, South Dakota, United States

Interest of Cryotherapy or Cortisone Aerosol Therapy in Early Post-operative Swallowing Disorders Following Total Thyroidectomy

Not Applicable

Completed

Conditions: Thyroidectomy
Post-operative Swallowing Disorders

Interventions: Procedure: thyroidectomy
Drug: cortisone aerosol
Other: cryotherapy
Drug: Dexamethasone acetate
Drug: paracetamol

First Posted Date: 2016-08-04

Last Posted Date: 2018-12-21

Lead Sponsor: Centre Hospitalier Universitaire Dijon

Target Recruit Count: 240

Registration Number: NCT02855866

Locations: 🇫🇷
CHU Dijon Bourgogne, Dijon, France

Cortisone Injection vs Trigger Point Dry Needling Fin the Treatment of Greater Trochanter Pain Syndrome: A Pilot Study

Phase 4

Completed

Conditions: Hip Injuries

Interventions: Procedure: Trigger Point Dry Needling
Drug: Cortisone Injection

First Posted Date: 2015-12-24

Last Posted Date: 2015-12-29

Lead Sponsor: Scott and White Hospital & Clinic

Target Recruit Count: 50

Registration Number: NCT02639039

Botulinum Toxin A Versus Steroids for the Treatment of Chronic Plantar Fasciitis

Not Applicable

Recruiting

Conditions: Plantar Fasciitis

Interventions: Drug: Saline
Drug: cortisone
Drug: Botulinum toxin A

First Posted Date: 2014-07-21

Last Posted Date: 2024-12-10

Lead Sponsor: Insel Gruppe AG, University Hospital Bern

Target Recruit Count: 54

Registration Number: NCT02196155

Locations: 🇨🇭
Dep, of Orthopaedic Surgery, Inselspital, University of Berne, Berne, Switzerland
🇨🇭
Department of Orthopaedic Surgery, Kantonsspital Lucerne, Lucerne, Switzerland

Non-surgical Treatment of Knee Osteoarthritis - a Comparison of Effects in 2200 Patients

Completed

Conditions: Knee Osteoarthritis

Interventions: Drug: Paracetamol and nonsteroidal antiinflammatory drug (NSAID)
Other: Physiotherapy
Drug: Cortisone Injection
Other: Others

First Posted Date: 2014-03-19

Last Posted Date: 2015-10-20

Lead Sponsor: Northern Orthopaedic Division, Denmark

Target Recruit Count: 2262

Registration Number: NCT02091830

Locations: 🇩🇰
Department of Orthopedic Surgery, Aalborg, Denmark

Effectiveness of Facet Joint Infiltration in Low Back Pain

Phase 3

Conditions: Low Back Pain

Interventions: Drug: Cortisone

First Posted Date: 2011-10-06

Last Posted Date: 2011-10-06

Lead Sponsor: Federal University of São Paulo

Target Recruit Count: 60

Registration Number: NCT01447160

Locations: 🇧🇷
Sao Paulo federal University, Sao Paulo, SP, Brazil

AMelioration of Angiotensin Converting Enzyme Inhibitor Induced Angioedema Study

Phase 2

Completed

Conditions: Angioedema

Interventions: Drug: Icatibant (subcutaneous) and plazebo (intravenous)
Drug: Cortisone + Clemastin (intravenous) and plazebo (subcutaneous)

First Posted Date: 2010-06-30

Last Posted Date: 2011-12-23

Lead Sponsor: Technical University of Munich

Registration Number: NCT01154361

Locations: 🇩🇪
Klinikum rechts der Isar Hals-Nasen-Ohrenklinik der TUM, Munich, Bavaria, Germany

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