Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

Warfarin and Vatalanib in Treating Patients With Advanced Solid Tumors

First Posted Date
2004-09-09
Last Posted Date
2020-08-05
Lead Sponsor
Jonsson Comprehensive Cancer Center
Target Recruit Count
24
Registration Number
NCT00091299
Locations
🇺🇸

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, California, United States

Combination Chemotherapy Plus Warfarin in Treating Patients With Prostate Cancer

Phase 2
Completed
Conditions
First Posted Date
2003-11-13
Last Posted Date
2013-01-16
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Registration Number
NCT00014352
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

Hormone Therapy Plus Radiation Therapy With or Without Combination Chemotherapy in Treating Patients With Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2020-10-22
Lead Sponsor
Radiation Therapy Oncology Group
Target Recruit Count
397
Registration Number
NCT00004054
Locations
🇺🇸

Lutheran General Cancer Care Center, Park Ridge, Illinois, United States

🇺🇸

Greater Baltimore Medical Center and Cancer Center, Baltimore, Maryland, United States

🇺🇸

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia, Pennsylvania, United States

and more 51 locations

Warfarin in Preventing Blood Clots in Cancer Patients With Central Venous Catheters

Not Applicable
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-08-07
Lead Sponsor
Cancer Research Campaign Clinical Trials Centre
Registration Number
NCT00024297
Locations
🇬🇧

Birmingham Heartlands and Solihull NHS Trust -Teaching, Birmingham, England, United Kingdom

🇬🇧

Essex County Hospital, Colchester, England, United Kingdom

🇬🇧

Princess Royal Hospital, Hull, England, United Kingdom

and more 35 locations

Warfarin Versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial

First Posted Date
2002-07-22
Last Posted Date
2014-09-05
Lead Sponsor
Columbia University
Target Recruit Count
2305
Registration Number
NCT00041938
Locations
🇺🇸

Albert Einstein Medical Center, Philadelphia, Pennsylvania, United States

🇺🇸

Penn Presbyterian Medical Center, Philadelphia, Pennsylvania, United States

🇺🇸

Morehouse School of Medicine, Atlanta, Georgia, United States

and more 61 locations

Aspirin Or Warfarin To Prevent Stroke

First Posted Date
2000-02-28
Last Posted Date
2006-06-06
Lead Sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Registration Number
NCT00004728
Locations
🇺🇸

Emory University, Atlanta, Georgia, United States

Treatment for Blood Clots in the Veins of the Legs

Phase 1
Completed
Conditions
First Posted Date
1999-11-04
Last Posted Date
2008-03-04
Lead Sponsor
National Institutes of Health Clinical Center (CC)
Target Recruit Count
20
Registration Number
NCT00001713
Locations
🇺🇸

National Institutes of Health Clinical Center (CC), Bethesda, Maryland, United States

Post Coronary Artery Bypass Graft (CABG) Study

First Posted Date
1999-10-28
Last Posted Date
2016-04-14
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000463
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