Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

D-dimer to Predict Recurrence in Patients With Multiple Episodes of Venous Thromboembolism

Not Applicable
Terminated
Conditions
First Posted Date
2007-01-30
Last Posted Date
2011-09-26
Lead Sponsor
Università degli Studi dell'Insubria
Target Recruit Count
73
Registration Number
NCT00428441
Locations
🇮🇹

University Of Insubria, Varese, Italy

Apixaban for the Prevention of Stroke in Subjects With Atrial Fibrillation

First Posted Date
2006-12-19
Last Posted Date
2018-07-03
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
20976
Registration Number
NCT00412984
Locations
🇺🇸

David Charles Mishkel, Md, Pa, Boca Raton, Florida, United States

🇺🇸

Heart Care Center, P.C., East Syracuse, New York, United States

🇺🇸

Elkhart Clinic, Llc, Elkhart, Indiana, United States

and more 263 locations

Study to Develop a Reliable Nomogram That Incorporates Clinical and Genetic Information

First Posted Date
2006-11-20
Last Posted Date
2013-08-30
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
344
Registration Number
NCT00401414
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach

First Posted Date
2006-06-28
Last Posted Date
2016-03-21
Lead Sponsor
Sanofi
Target Recruit Count
3202
Registration Number
NCT00345618
Locations
🇷🇺

Sanofi-Aventis Admnistrative Office, Moscow, Russian Federation

🇬🇧

Sanofi-Aventis Administrative Office, Guildford Surrey, United Kingdom

🇦🇺

sanofi-aventis Australia & New Zealand administrative office, Macquarie Park, New South Wales, Australia

and more 1 locations

Secondary Prevention of Venous Thrombo Embolism (VTE).

Phase 3
Completed
Conditions
Interventions
First Posted Date
2006-05-24
Last Posted Date
2014-05-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
2867
Registration Number
NCT00329238
Locations
🇺🇸

1160.47.01030 Boehringer Ingelheim Investigational Site, Grand Forks, North Dakota, United States

🇨🇦

1160.47.02019 Boehringer Ingelheim Investigational Site, Toronto, Ontario, Canada

🇲🇽

1160.47.52030 Boehringer Ingelheim Investigational Site, Guadalajara, Jal., Mexico

and more 272 locations

Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2005-12-14
Last Posted Date
2014-12-08
Lead Sponsor
University of California, San Diego
Registration Number
NCT00265408
Locations
🇺🇸

UCSD Medical Center, San Diego, California, United States

Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) With Dabigatran Etexilate

First Posted Date
2005-12-07
Last Posted Date
2019-04-17
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
18113
Registration Number
NCT00262600
Locations
🇸🇪

1160.26.1633 Sahlgrenska Sjukhuset, Göteboerg, Sweden

🇺🇸

1160.26.0278 Boehringer Ingelheim Investigational Site, Bridgeport, Connecticut, United States

🇺🇸

1160.26.0358 Boehringer Ingelheim Investigational Site, Melbourne, Florida, United States

and more 981 locations

The Association of Warfarin Dosage and Plasma Enantiomer Concentration With the Gene Polymorphisms of CYP and VKOR

Not Applicable
Conditions
First Posted Date
2005-11-02
Last Posted Date
2005-11-02
Lead Sponsor
National Taiwan University Hospital
Target Recruit Count
120
Registration Number
NCT00247702
Locations
🇨🇳

National Taiwan University Hospital, Taipei, Taiwan

Treatment of Upper Extremity Deep-Vein Thrombosis

First Posted Date
2005-10-28
Last Posted Date
2013-02-21
Lead Sponsor
University of Oklahoma
Target Recruit Count
67
Registration Number
NCT00245856
Locations
🇺🇸

Department of Veterans Affairs Medical Center, Oklahoma City, Oklahoma, United States

🇺🇸

University of Oklahoma Health Science Center, Oklahoma City, Oklahoma, United States

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