Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

Extended Duration of Oral Anticoagulant Therapy After a First Episode of Idiopathic Pulmonary Embolism: a Randomized Controlled Trial. "PADIS-PE" Study.

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-08-25
Last Posted Date
2017-01-12
Lead Sponsor
University Hospital, Brest
Target Recruit Count
374
Registration Number
NCT00740883
Locations
🇫🇷

Brest University Hospital, Brest, France

Prolonged Anticoagulation After a First Episod of Idiopathic Proximal Deep Vein Thrombosis (PADIS TVP)

First Posted Date
2008-08-25
Last Posted Date
2017-01-12
Lead Sponsor
University Hospital, Brest
Target Recruit Count
104
Registration Number
NCT00740493
Locations
🇫🇷

Centre Hospitalier de Saint Brieuc, Saint Brieuc, France

🇫🇷

Centre Hospitalier de Cornouaille, Quimper, France

🇫🇷

CHU de Rennes, Rennes, France

and more 11 locations

Assessing the Clinical Benefits of a Pharmacogenetics-Guided Dosing Regiment for Calculating Warfarin Maintenance Dose

First Posted Date
2008-06-19
Last Posted Date
2016-06-07
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
320
Registration Number
NCT00700895
Locations
🇲🇾

University of Malaya Medical Centre, Kuala Lumpur, Malaysia

🇸🇬

National University Hospital, Singapore, Singapore

Patent Foramen Ovale in Cryptogenic Stroke Study

First Posted Date
2008-06-13
Last Posted Date
2011-09-15
Lead Sponsor
Columbia University
Target Recruit Count
630
Registration Number
NCT00697151
Locations
🇺🇸

Columbia College of Physicians and Surgeons, New York, New York, United States

Drug Interaction Study Between AZD3480 and Warfarin

First Posted Date
2008-06-03
Last Posted Date
2009-07-02
Lead Sponsor
AstraZeneca
Target Recruit Count
26
Registration Number
NCT00689637
Locations
🇸🇪

Research SIte, Uppsala, Sweden

Effect of Warfarin in the Treatment of Metachromatic Leukodystrophy

Not Applicable
Completed
Conditions
First Posted Date
2008-05-23
Last Posted Date
2011-03-21
Lead Sponsor
The Cooper Health System
Target Recruit Count
10
Registration Number
NCT00683189
Locations
🇺🇸

Cooper University Hospital, Camden, New Jersey, United States

Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-05-20
Last Posted Date
2014-05-19
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
2589
Registration Number
NCT00680186
Locations
🇨🇦

1160.46.02021 Boehringer Ingelheim Investigational Site, Victoria, British Columbia, Canada

🇨🇦

1160.46.02004 Boehringer Ingelheim Investigational Site, Saint John, New Brunswick, Canada

🇨🇦

1160.46.02019 Boehringer Ingelheim Investigational Site, Toronto, Ontario, Canada

and more 217 locations

Fondaparinux for the Treatment of Heparin-Induced Thrombocytopenia (HIT)

First Posted Date
2008-05-07
Last Posted Date
2019-11-08
Lead Sponsor
University of Louisville
Target Recruit Count
3
Registration Number
NCT00673439
Locations
🇺🇸

University of Louisville Hospital, Louisville, Kentucky, United States

Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism

First Posted Date
2008-03-26
Last Posted Date
2014-04-21
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
5614
Registration Number
NCT00643201
Locations
🇺🇸

Pasadena Center For Medical Research, St. Petersburg, Florida, United States

🇺🇸

Great Falls Clinic, Llp, Great Falls, Montana, United States

🇺🇸

Infectious Disease Of Indiana Psc, Carmel, Indiana, United States

and more 71 locations

Prevention of Venous Thrombosis After Permanent Transvenous Leads Implantation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-02-22
Last Posted Date
2012-10-26
Lead Sponsor
University of Sao Paulo
Target Recruit Count
101
Registration Number
NCT00621491
Locations
🇧🇷

Heart Institute (InCor) - Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, SP, Brazil

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