Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

Replication of the EINSTEIN-DVT Anticoagulant Trial in Healthcare Claims Data

First Posted Date
2021-02-03
Last Posted Date
2023-07-28
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
78605
Registration Number
NCT04736420
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Replication of the AMPLIFY Anticoagulant Trial in Healthcare Claims Data

First Posted Date
2021-02-03
Last Posted Date
2023-07-27
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
19002
Registration Number
NCT04736719
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data

First Posted Date
2021-02-03
Last Posted Date
2023-08-01
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
5350
Registration Number
NCT04735523
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

STOPping Anticoagulation for Isolated or Incidental Subsegmental Pulmonary Embolism

First Posted Date
2021-01-27
Last Posted Date
2021-09-29
Lead Sponsor
University of Birmingham
Target Recruit Count
1466
Registration Number
NCT04727437
Locations
🇬🇧

Surrey & Sussex Healthcare NHS Trust, Redhill, United Kingdom

A Drug Interaction Study of Danicopan

First Posted Date
2021-01-14
Last Posted Date
2021-01-14
Lead Sponsor
Alexion Pharmaceuticals, Inc.
Target Recruit Count
52
Registration Number
NCT04709094
Locations
🇺🇸

Clinical Study Site, Tempe, Arizona, United States

NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications

First Posted Date
2020-12-10
Last Posted Date
2024-01-26
Lead Sponsor
Malmö University
Target Recruit Count
216
Registration Number
NCT04662515
Locations
🇸🇪

Skåne University Hospital, Helsingborg, Sweden

🇸🇪

Department of Oral and Maxillofacial Surgery and Oral Medicine, Faculty of Odontology, Malmö University, Malmö, Sweden

Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy(ESAWAAPT)

First Posted Date
2020-11-27
Last Posted Date
2023-12-21
Lead Sponsor
Northern Jiangsu People's Hospital
Target Recruit Count
120
Registration Number
NCT04645550
Locations
🇨🇳

Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu, China

Replication of the RELY Anticoagulant Trial in Healthcare Claims Data

First Posted Date
2020-10-19
Last Posted Date
2023-07-27
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
78140
Registration Number
NCT04593043
Locations
🇺🇸

Brigham And Women's Hospital, Boston, Massachusetts, United States

Replication of the ARISTOTLE Anticoagulant Trial in Healthcare Claims Data

Completed
Conditions
Interventions
First Posted Date
2020-10-19
Last Posted Date
2023-07-27
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
220518
Registration Number
NCT04593030
Locations
🇺🇸

Brigham And Women's Hospital, Boston, Massachusetts, United States

Replication of the ROCKET-AF Anticoagulant Trial in Healthcare Claims Data

First Posted Date
2020-10-19
Last Posted Date
2023-07-28
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
102636
Registration Number
NCT04593056
Locations
🇺🇸

Brigham And Women's Hospital, Boston, Massachusetts, United States

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