Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

Rivaroxaban for Children With Giant Coronary Artery Aneurysms After Kawasaki Disease

First Posted Date
2022-12-09
Last Posted Date
2024-07-09
Lead Sponsor
Children's Hospital of Fudan University
Target Recruit Count
100
Registration Number
NCT05643651
Locations
🇨🇳

Children's Hospital of Fudan University, Shanghai, Shanghai, China

A Drug Interaction Study of LY3871801 in Healthy Participants

First Posted Date
2022-11-02
Last Posted Date
2023-04-18
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
39
Registration Number
NCT05602675
Locations
🇺🇸

Covance Dallas, Dallas, Texas, United States

Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis

First Posted Date
2022-09-14
Last Posted Date
2022-09-14
Lead Sponsor
Sung-Hwan Kim
Target Recruit Count
240
Registration Number
NCT05540587
Locations
🇰🇷

Bucheon St. Mary's hospital, Bucheon, Korea, Republic of

🇰🇷

Yeouido St. Mary's hospital, Yeongdeungpo-gu, Seoul, Korea, Republic of

🇰🇷

Seoul St. Mary's Hospital, Seoul, Seocho-gu, Korea, Republic of

and more 4 locations

A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2022-07-29
Last Posted Date
2022-11-08
Lead Sponsor
Idorsia Pharmaceuticals Ltd.
Target Recruit Count
18
Registration Number
NCT05480488
Locations
🇩🇪

Nuvisan GmbH, Neu-Ulm, Germany

A Drug-Drug Interaction (DDI) Study of LY3437943 in Obese Participants

First Posted Date
2022-07-06
Last Posted Date
2023-04-18
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
32
Registration Number
NCT05445232
Locations
🇺🇸

Covance Dallas, Dallas, Texas, United States

🇺🇸

Covance Clinical Research Unit, Daytona Beach, Florida, United States

Safety and Effectiveness of Apixaban in Very Elderly Patients With Non-valvular Atrial Fibrillation (NVAF) Compared to Warfarin Using Administrative Claims Data

First Posted Date
2022-06-30
Last Posted Date
2024-05-20
Lead Sponsor
Pfizer
Target Recruit Count
77814
Registration Number
NCT05438888
Locations
🇯🇵

Pfizer Site, Tokyo, Japan

Safety and Effectiveness of Apixaban Compared to Warfarin in Secondary Prevention in Patients With Atrial Fibrillation

First Posted Date
2022-04-11
Last Posted Date
2024-01-11
Lead Sponsor
Pfizer
Target Recruit Count
193565
Registration Number
NCT05321810
Locations
🇯🇵

Pfizer, Tokyo, Japan

Cost-effectiveness Analysis Between Two Anticoagulation Strategies for Atrial Fibrillation in the Postoperative Period of Coronary Artery Bypass Graft Surgery

First Posted Date
2022-03-29
Last Posted Date
2022-03-29
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
50
Registration Number
NCT05300555
Locations
🇧🇷

Heart Institute - University of São Paulo, São paulo, Sao Paulo, Brazil

Apixaban in Patients With Left Ventricular Thrombus

Phase 3
Completed
Conditions
Interventions
First Posted Date
2022-01-26
Last Posted Date
2022-01-26
Lead Sponsor
Saud Al Babtain Cardiac Center
Target Recruit Count
50
Registration Number
NCT05208398
Locations
🇸🇦

Saud AlBabtain Cardiac Center, Dammam, Saudi Arabia

Treatment Patterns and Bleeding Risk of Anticoagulants in Patients With Venous Thromboembolism in Korea

First Posted Date
2021-08-26
Last Posted Date
2023-08-03
Lead Sponsor
Pfizer
Target Recruit Count
55759
Registration Number
NCT05022563
Locations
🇰🇷

Seoul National University Bundang Hospital, Seongnam-si, Korea, Republic of

🇰🇷

Sungkyunkwan University, Suwon-si, Korea, Republic of

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