Warfarin

Generic Name
Warfarin
Brand Names
Coumadin, Jantoven
Drug Type
Small Molecule
Chemical Formula
C19H16O4
CAS Number
81-81-2
Unique Ingredient Identifier
5Q7ZVV76EI
Background

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally, including its ...

Indication

Indicated for:

1) Prophylaxis and treatment of venous thromboembolism and related pulmonary embolism.

2) Prophylaxis and treatment of thromboembolism associated with atrial fibrillation.

3) Prophylaxis and treatment of thromboembolism associated with cardiac valve replacement.
...

Associated Conditions
Myocardial Infarction, Pulmonary Embolism, Stroke, Systemic Embolism, Thromboembolism, Transient Ischemic Attack, Venous Thrombosis (Disorder)
Associated Therapies
-

"ORBIT" Versus "HAS-BLED" Scores in Predicting Major Bleeding in Patients With Atrial Fibrillation Receiving Oral Anticoagulants.

First Posted Date
2023-08-03
Last Posted Date
2023-08-03
Lead Sponsor
Sohag University
Target Recruit Count
100
Registration Number
NCT05975320

Safety and Efficacy of Rivaroxaban and Apixaban in Comparison to Warfarin in Left Ventricular Clot- Clinical Trial

First Posted Date
2023-08-02
Last Posted Date
2023-08-02
Lead Sponsor
Peshawar Institute of Cardiology
Target Recruit Count
141
Registration Number
NCT05973188
Locations
🇵🇰

Peshawar Institute of Cardiology, Peshawar, KPK, Pakistan

Study to Investigate the Effect of Rocatinlimab (AMG 451) on the Pharmacokinetics of Multiple Cytochrome P450 (CYP450) Substrates in Participants With Moderate to Severe Atopic Dermatitis

First Posted Date
2023-06-06
Last Posted Date
2024-11-07
Lead Sponsor
Amgen
Target Recruit Count
21
Registration Number
NCT05891119
Locations
🇺🇸

Direct Helpers Research Center (DHRC), Hialeah, Florida, United States

🇺🇸

Velocity Clinical Research -Spartanburg, Spartanburg, South Carolina, United States

🇺🇸

DermDox Dermatology Centers, PC - Sugarloaf, Nashville, Tennessee, United States

and more 4 locations

A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

First Posted Date
2023-04-18
Last Posted Date
2023-11-14
Lead Sponsor
Innovent Biologics (Suzhou) Co. Ltd.
Target Recruit Count
48
Registration Number
NCT05815680
Locations
🇨🇳

Aerospace Center Hospital, Beijing, Beijing, China

Treatment Patterns Among Patients With Venous Thromboembolism in the United States

First Posted Date
2023-04-03
Last Posted Date
2024-11-22
Lead Sponsor
Pfizer
Target Recruit Count
13945
Registration Number
NCT05795062
Locations
🇺🇸

Pfizer, New York, New York, United States

Anticoagulation in Post MI LV Thrombus Trial in Nepal

First Posted Date
2023-04-03
Last Posted Date
2024-04-17
Lead Sponsor
Shahid Gangalal National Heart Centre
Target Recruit Count
196
Registration Number
NCT05794399
Locations
🇳🇵

Nepal Health Research Council, Kathmandu, Bagmati, Nepal

Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy

First Posted Date
2023-03-23
Last Posted Date
2023-08-07
Lead Sponsor
China National Center for Cardiovascular Diseases
Target Recruit Count
202
Registration Number
NCT05782270
Locations
🇨🇳

Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing, China

A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

First Posted Date
2023-02-23
Last Posted Date
2024-11-18
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
30
Registration Number
NCT05741385
Locations
🇩🇪

CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany

Rivaroxaban vErsus Warfarin for Antithrombotic TheRapy in Patients With LeFt Ventricular Thrombus After Acute STEMI

First Posted Date
2023-01-30
Last Posted Date
2023-04-07
Lead Sponsor
Rajaie Cardiovascular Medical and Research Center
Target Recruit Count
50
Registration Number
NCT05705089
Locations
🇮🇷

Rajaie Cardiovascular Medical and Research Center, Tehran, Iran, Islamic Republic of

🇮🇷

Tehran Heart Center, Tehran, Iran, Islamic Republic of

Telitacicept Followed With Rituximab Therapy on APS Secondary to SLE

First Posted Date
2022-12-09
Last Posted Date
2022-12-09
Lead Sponsor
Qilu Hospital of Shandong University
Target Recruit Count
80
Registration Number
NCT05644210
Locations
🇨🇳

Qilu Hospital, Jinan, Shandong, China

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