Somatotropin

Generic Name
Somatotropin
Brand Names
Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
Drug Type
Biotech
Chemical Formula
-
CAS Number
12629-01-5
Unique Ingredient Identifier
NQX9KB6PCL
Background

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...

Indication

Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...

Associated Conditions
Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
Associated Therapies
-

Growth Hormone Deficiency in Mild Traumatic Brain Injury

First Posted Date
2022-12-21
Last Posted Date
2022-12-21
Lead Sponsor
University of Calgary
Target Recruit Count
20
Registration Number
NCT05660356

Growth Hormone to Improve the Clinical Outcome of Assisted Fertility in Young Patients With Decreased Ovarian Reserve

Not Applicable
Recruiting
Conditions
Interventions
First Posted Date
2022-10-18
Last Posted Date
2022-10-24
Lead Sponsor
Nanjing University
Target Recruit Count
120
Registration Number
NCT05585177
Locations
🇨🇳

Reproductive Medicine Center, The affiliated Drum Towel Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China

Effect of GH Supplementation on the Blastocyst Euploid Rate in AMA Patients--A Retrospective Cohort Study

First Posted Date
2022-10-12
Last Posted Date
2023-02-21
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
692
Registration Number
NCT05574894
Locations
🇨🇳

Shanghai JIAI Genetics and IVF Institute, Shanghai, Shanghai, China

Effect of GH on the Blastocyst Euploid Rate in AMA Patients

First Posted Date
2022-07-07
Last Posted Date
2022-10-13
Lead Sponsor
ShangHai Ji Ai Genetics & IVF Institute
Target Recruit Count
400
Registration Number
NCT05447208
Locations
🇨🇳

Shanghai JIAI Genetics and IVF Institute, Shanghai, Shanghai, China

Growth Hormone in a Patient With a Dominant-Negative GHR Mutation

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-05-19
Last Posted Date
2024-02-13
Lead Sponsor
Children's National Research Institute
Target Recruit Count
1
Registration Number
NCT05382637
Locations
🇺🇸

Children's National Hospital, Washington, District of Columbia, United States

Growth Hormone Replacement in Veterans With GWI and AGHD (GWIT)

First Posted Date
2022-05-02
Last Posted Date
2024-07-15
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
20
Registration Number
NCT05355272
Locations
🇺🇸

VA Puget Sound Healthcare System, Seattle, Washington, United States

🇺🇸

Michael E. DeBakey VA Medical Center, Houston, Texas, United States

A Study to Evaluate the Efficacy and Safety of Recombinant Human Growth Hormone in Children With Achondroplasia

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2022-04-29
Last Posted Date
2023-02-28
Lead Sponsor
Changchun GeneScience Pharmaceutical Co., Ltd.
Target Recruit Count
38
Registration Number
NCT05353192
Locations
🇨🇳

Children's Hospital of Fudan University, Shanghai, Shanghai, China

Effect of GH Administration in Poor Responders Undergoing Intracytoplasmic Sperm Injection (ICSI)

Phase 4
Completed
Conditions
Interventions
First Posted Date
2022-03-16
Last Posted Date
2022-08-09
Lead Sponsor
Alexandria University
Target Recruit Count
160
Registration Number
NCT05281341
Locations
🇪🇬

faculty of medicine, Alexandria University, Alexandria, Egypt

Growth Hormone in Decompensated Liver Cirrhosis

First Posted Date
2022-02-23
Last Posted Date
2022-03-29
Lead Sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
Target Recruit Count
80
Registration Number
NCT05253287
Locations
🇮🇳

Postgraduate Institute of Medical education and Research, Chandigarh, UT, India

A Controlled Trial of Growth Hormone in Phelan-McDermid Syndrome and Idiopathic Autism

First Posted Date
2022-01-11
Last Posted Date
2024-05-10
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
45
Registration Number
NCT05187377
Locations
🇺🇸

Seaver Autism Center for Research & Treatment, New York, New York, United States

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