Somatotropin
- Generic Name
- Somatotropin
- Brand Names
- Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 12629-01-5
- Unique Ingredient Identifier
- NQX9KB6PCL
- Background
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...
- Indication
Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...
- Associated Conditions
- Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
- Associated Therapies
- -
Effectiveness of Recombinant Human Growth Hormone Therapy for Children With PMS
- Conditions
- Interventions
- First Posted Date
- 2021-11-03
- Last Posted Date
- 2022-10-10
- Lead Sponsor
- Affiliated Hospital of Jiangnan University
- Target Recruit Count
- 6
- Registration Number
- NCT05105685
- Locations
- 🇨🇳
Affiliated Hospital of JiangNan University, Department of Pediatrics, Wuxi, Jiangsu, China
Growth Hormone Pretreatment in Poseidon Type IV Undergoing ICSI Using Minimal Induction Protocol: A Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2021-10-22
- Last Posted Date
- 2021-10-22
- Lead Sponsor
- Ain Shams Maternity Hospital
- Target Recruit Count
- 132
- Registration Number
- NCT05089344
- Locations
- 🇪🇬
AinShams University, Cairo, Egypt
Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)
- Conditions
- Interventions
- First Posted Date
- 2021-04-30
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 172
- Registration Number
- NCT04867317
- Locations
- 🇺🇸
Miami VA Healthcare System, Miami, FL, Miami, Florida, United States
🇺🇸Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia, United States
🇺🇸Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota, United States
A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency
- Conditions
- Interventions
- First Posted Date
- 2020-11-04
- Last Posted Date
- 2023-12-21
- Lead Sponsor
- Ascendis Pharma Endocrinology Division A/S
- Target Recruit Count
- 264
- Registration Number
- NCT04615273
- Locations
- 🇬🇧
Ascendis Pharma Investigational Site, Leeds, United Kingdom
Growth Hormone in Obese Cases With Covid-19
- First Posted Date
- 2020-08-31
- Last Posted Date
- 2020-09-16
- Lead Sponsor
- ClinAmygate
- Registration Number
- NCT04532554
- Locations
- 🇪🇬
Asalam, Maadi, Cairo, Egypt
Growth Hormone in Ischemic Heart Failure
- Conditions
- Interventions
- First Posted Date
- 2020-06-09
- Last Posted Date
- 2020-06-09
- Lead Sponsor
- Göteborg University
- Target Recruit Count
- 37
- Registration Number
- NCT04420481
To Explore the Effect of GH on Outcomes of IVF and Telomerase Activity of Granulosa Cells in Women With POR
- Conditions
- Interventions
- First Posted Date
- 2020-05-12
- Last Posted Date
- 2020-05-21
- Lead Sponsor
- Guangzhou First People's Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT04384744
To Explore the Effect of GH Pretreatment on Clinical Outcomes in Patients With Low Ovarian Reserve
- Conditions
- Interventions
- First Posted Date
- 2020-05-12
- Last Posted Date
- 2020-05-21
- Lead Sponsor
- Guangzhou First People's Hospital
- Target Recruit Count
- 114
- Registration Number
- NCT04384783
6x3 Crossover, Bioavailability, Safety and Tolerability Among Different Eutropin Formulations in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2019-09-11
- Last Posted Date
- 2020-03-24
- Lead Sponsor
- LG Chem
- Target Recruit Count
- 24
- Registration Number
- NCT04085224
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Growth Hormone Treatment in Children With Phelan McDermid Syndrome
- Conditions
- Interventions
- First Posted Date
- 2019-07-01
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Swathi Sethuram
- Target Recruit Count
- 6
- Registration Number
- NCT04003207
- Locations
- 🇺🇸
Seaver Autism Center, New York, New York, United States
Drug Development Updates
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