Somatotropin

Generic Name
Somatotropin
Brand Names
Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
Drug Type
Biotech
Chemical Formula
-
CAS Number
12629-01-5
Unique Ingredient Identifier
NQX9KB6PCL
Background

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...

Indication

Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...

Associated Conditions
Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
Associated Therapies
-

Adrenal Function in GHD Children

First Posted Date
2017-06-29
Last Posted Date
2017-06-29
Lead Sponsor
University of Palermo
Target Recruit Count
30
Registration Number
NCT03203356
Locations
🇮🇹

Endocrinology - University of Palermo, Palermo, Italy

Study of Testosterone and rHGH in FSHD

First Posted Date
2017-04-21
Last Posted Date
2023-05-16
Lead Sponsor
University of Rochester
Target Recruit Count
20
Registration Number
NCT03123913
Locations
🇺🇸

University of Rochester, Rochester, New York, United States

Impact of Recombinant Human Growth Hormone on HIV Persistence

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2017-03-27
Last Posted Date
2024-03-13
Lead Sponsor
McGill University Health Centre/Research Institute of the McGill University Health Centre
Target Recruit Count
22
Registration Number
NCT03091374
Locations
🇨🇦

Mcgill University Health Center, Montreal, Quebec, Canada

Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients

First Posted Date
2017-01-31
Last Posted Date
2023-02-13
Lead Sponsor
The University of Texas Medical Branch, Galveston
Target Recruit Count
13
Registration Number
NCT03038594
Locations
🇺🇸

University of Texas Medical Branch, Galveston, Texas, United States

Three-times-weekly Versus Daily Growth Hormone (GH) Treatment in naïve GH-deficient Children

Phase 3
Completed
Conditions
Interventions
First Posted Date
2017-01-26
Last Posted Date
2017-10-27
Lead Sponsor
University of Palermo
Target Recruit Count
32
Registration Number
NCT03033121
Locations
🇮🇹

Endocrinology - University of Palermo, Palermo, Italy

The Effect of Growth Hormone in Assisted Reproductive Technology Clinical Outcome of Poor Responder

Phase 4
Conditions
Interventions
First Posted Date
2017-01-23
Last Posted Date
2017-01-23
Lead Sponsor
Sun Yat-sen University
Target Recruit Count
80
Registration Number
NCT03027843

Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.

First Posted Date
2017-01-10
Last Posted Date
2019-01-03
Lead Sponsor
LG Life Sciences
Target Recruit Count
116
Registration Number
NCT03015909
Locations
🇰🇷

Ajou university hospital, Suwon, Gyeong-gi, Korea, Republic of

Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

First Posted Date
2016-11-18
Last Posted Date
2024-07-24
Lead Sponsor
OPKO Health, Inc.
Target Recruit Count
224
Registration Number
NCT02968004
Locations
🇮🇳

Manipal Hospital, Bengaluru, Karnataka, India

🇨🇳

Tri-Service General Hospital, Taipei, Taiwan

🇺🇸

University of Massachusettes, Worcester, Massachusetts, United States

and more 78 locations

Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

First Posted Date
2016-10-13
Last Posted Date
2016-10-14
Lead Sponsor
Cambridge University Hospitals NHS Foundation Trust
Target Recruit Count
24
Registration Number
NCT02931591

Lipolytic Effects of GH in Human Subjects in Vivo

First Posted Date
2016-05-25
Last Posted Date
2020-03-26
Lead Sponsor
University of Aarhus
Target Recruit Count
9
Registration Number
NCT02782221
Locations
🇩🇰

University Hospital of Aarhus, Aarhus, Denmark

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