DeepMed Research

Hydrogen

Generic Name: Hydrogen

Drug Type: Small Molecule

Chemical Formula: H_₂

CAS Number: 1333-74-0

Unique Ingredient Identifier: 7YNJ3PO35Z

Background: Hydrogen is under investigation in clinical trial NCT02830854 (Molecular Hydrogen for Cognitive Function and Performance in Elderly).

Clinical Trials

Hydrogen's Feasibility and Safety as a Therapy in ECPR

Phase 1

Recruiting

Conditions: Cardiac Arrest
Extracorporeal Membrane Oxygenation
Reperfusion Injury

Interventions: Drug: Hydrogen
Other: Usual care

First Posted Date: 2022-10-10

Last Posted Date: 2024-08-07

Lead Sponsor: Boston Children's Hospital

Target Recruit Count: 53

Registration Number: NCT05574296

Locations: 🇺🇸
Boston Children's Hospital, Boston, Massachusetts, United States

Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.

Not Applicable

Completed

Conditions: Post Operative Pain

Interventions: Drug: Propolis
Drug: hydrogen peroxide 35%
Other: fluoride varnish

First Posted Date: 2022-10-06

Last Posted Date: 2022-10-06

Lead Sponsor: Dow University of Health Sciences

Target Recruit Count: 90

Registration Number: NCT05569590

Locations: 🇵🇰
Fatima Soomro, Karachi, Sindh, Pakistan

To Evaluate the Safety of Treating Rheumatologic and Metabolic Patients With Molecular Hydrogen Supplement.

Phase 1

Conditions: Autoimmune Diseases
Metabolic Disease

Interventions: Drug: Hydrogen

First Posted Date: 2022-01-19

Last Posted Date: 2022-02-10

Lead Sponsor: HoHo Biotech

Target Recruit Count: 30

Registration Number: NCT05196295

Locations: 🇨🇳
Min-Sheng Gereral hospital, Taoyuan, Taiwan

To Evaluate the Safety of Treating Autoimmune Diseases With Molecular Hydrogen Supplement

Phase 1

Conditions: Autoimmune Diseases

Interventions: Drug: Hydrogen

First Posted Date: 2021-11-10

Last Posted Date: 2021-11-10

Lead Sponsor: HoHo Biotech

Target Recruit Count: 27

Registration Number: NCT05116215

Locations: 🇨🇳
Tri-Service General Hospital, Taipei, Taiwan

Hydrogen Peroxide Trial to Investigate the Efficacy of 30%H2O2 as a Topical Application Before Definitive Treatment

Phase 2

Conditions: Squamous Cell Carcinoma of Skin Differentiated
Basal Cell Carcinoma

Interventions: Drug: Hydrogen Peroxide 30 % Topical Solution

First Posted Date: 2021-06-18

Last Posted Date: 2022-08-30

Lead Sponsor: Lawson Health Research Institute

Target Recruit Count: 51

Registration Number: NCT04929535

Locations: 🇨🇦
London Regional Cancer Program, London, Ontario, Canada

Clinical Effectiveness of 5 Different Mouthwashes in the Treatment of Generalised Gingivitis

Not Applicable

Completed

Conditions: Gingivitis

Interventions: Drug: Hydrogen peroxide 0,8 %
Drug: Essential oils
Drug: Essential oils in combination with chlorhexidine 0,12%
Drug: Chlorhexidine 0,20 % in combination with aroma oils
Drug: Placebo mouthwash
Drug: Prebiotic

First Posted Date: 2021-02-01

Last Posted Date: 2021-02-01

Lead Sponsor: Plovdiv Medical University

Target Recruit Count: 180

Registration Number: NCT04733196

Locations: 🇧🇬
Blagovesta Yaneva, Plovdiv, Bulgaria

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

Phase 4

Completed

Conditions: Mouthwashes
SARS-CoV-2
Viral Load
Polymerase Chain Reaction
Coronavirus
Saliva
COVID-19
Covid19

Interventions: Drug: Distilled Water
Drug: 1.5% Hydrogen Peroxide (H2O2)
Drug: 0.1% Sodium Hypochlorite
Drug: 0.075% Cetylpyridinium Chloride (CPC)
Other: No rinse group
Drug: 1% Povidone Iodine (PVP-I)

First Posted Date: 2021-01-22

Last Posted Date: 2022-07-21

Lead Sponsor: King Abdulaziz University

Target Recruit Count: 90

Registration Number: NCT04721457

Locations: 🇸🇦
Alhamra TETAMMAN clinic (PHC), Jeddah, Saudi Arabia

Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19

Phase 4

Conditions: COVID-19

Interventions: Drug: 1% Hydrogen Peroxide
Drug: 0.5% Povidone Iodine
Drug: 0.9% Normal Saline
Drug: 0.12% Chlorhexidine Gluconate Mouth Rinse

First Posted Date: 2020-10-27

Last Posted Date: 2020-10-27

Lead Sponsor: Ohio State University

Target Recruit Count: 60

Registration Number: NCT04603794

Locations: 🇺🇸
The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

Mouth Rinses for Inactivation of COVID-19

Phase 2

Terminated

Conditions: Covid19
Coronavirus Infection
SARS-CoV-2 Infection

Interventions: Drug: 1.5% w/v Hydrogen Peroxide
Other: 0.9% w/v NaCL Saline
Drug: 27% Ethanol plus essential oils
Drug: 0.5% w/v Povidone-iodide
Drug: 0.12% Chlorohexidine Gluconate
Drug: 0.075% Cetylpyridinium Chloride

First Posted Date: 2020-10-14

Last Posted Date: 2024-03-25

Lead Sponsor: University of North Carolina, Chapel Hill

Target Recruit Count: 128

Registration Number: NCT04584684

Locations: 🇺🇸
General and Oral Health Center, Chapel Hill, North Carolina, United States

Effect of a Hydrogen-Peroxide and Hyaluronic-Acid Mouthwash (BMG0703) in the Treatment of Periodontitis

Phase 3

Conditions: Periodontitis
Pocket, Periodontal
Bleeding Gum

Interventions: Drug: Placebo
Drug: Hydrogen Peroxide and Hyaluronic acid filming formulation
Drug: Chlorhexidine 0.2%

First Posted Date: 2020-06-25

Last Posted Date: 2020-06-25

Lead Sponsor: University of Milan

Target Recruit Count: 50

Registration Number: NCT04446533

Locations: 🇮🇹
UOC Maxillofacial Surgery and Odontology, University of Milan, Milan, Lombardy, Italy

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