DeepMed Research

Hypochlorite

Generic Name: Hypochlorite

Drug Type: Small Molecule

Chemical Formula: ClO

CAS Number: 14380-61-1

Unique Ingredient Identifier: T5UM7HB19N

Background: Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions.

Indication: Indicated for over-the-counter use as a disinfectant agent in the sodium hypochlorite form.

Associated Therapies: Skin disinfection

Clinical Trials

Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars

Not Applicable

Not yet recruiting

Conditions: Dental Caries
Pulp Necrosis
Pediatric Dentistry
Primary Tooth Pulpectomy
Endodontic Infection

Interventions: Drug: Sodium hypochlorite
Biological: Moringa Oleifera Leaf Extract

First Posted Date: 2025-05-14

Last Posted Date: 2025-05-14

Lead Sponsor: Cairo University

Target Recruit Count: 38

Registration Number: NCT06971055

Locations: 🇪🇬
Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University, Cairo, Egypt

Comparison of Effectiveness of Disinfectants

Phase 1

Completed

Conditions: Root Canal Infection

Interventions: Drug: Sodium Hypochlorite
Drug: Chlorhexidine

First Posted Date: 2025-02-06

Last Posted Date: 2025-02-06

Lead Sponsor: Armed Forces Institute of Dentistry, Pakistan

Target Recruit Count: 124

Registration Number: NCT06811779

Locations: 🇵🇰
Armed Forces Institute of Dentistry, Rawalpindi, Punjab, Pakistan

Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy Techniques

Phase 4

Completed

Conditions: Pulp Mummification
Pulp Disease, Dental

Interventions: Drug: Sodium Hypochlorite Solution
Drug: Formocresol
Device: Diode laser

First Posted Date: 2023-08-21

Last Posted Date: 2024-04-19

Lead Sponsor: University of Sulaimani

Target Recruit Count: 60

Registration Number: NCT06002646

Locations: 🇮🇶
Wasan Adil Fadhil, Sulaymaniyah, Iraq

Role of Propolis Endodontic Irrigant on Post-Operative Pain

Phase 3

Completed

Conditions: Post-operative Pain
Symptomatic Irreversible Pulpitis

Interventions: Drug: Propolis 20%
Drug: Sodium hypochlorite 5.25%

First Posted Date: 2023-08-03

Last Posted Date: 2023-09-07

Lead Sponsor: Dow University of Health Sciences

Target Recruit Count: 44

Registration Number: NCT05974748

Locations: 🇵🇰
Dow International Dental College, Karachi, Sindh, Pakistan

Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Phase 2

Conditions: Necrotic Pulp

Interventions: Dietary Supplement: Moringa oleifera leaf
Drug: Sodium hypochlorite

First Posted Date: 2022-04-27

Last Posted Date: 2022-08-09

Lead Sponsor: Cairo University

Target Recruit Count: 30

Registration Number: NCT05348824

Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants

Phase 2

Completed

Conditions: Irreversible Pulpitis

Interventions: Drug: Sodium Hypochlorite
Drug: Polyhexamethylene biguanide

First Posted Date: 2022-04-01

Last Posted Date: 2023-02-21

Lead Sponsor: Altamash Institute of Dental Medicine

Target Recruit Count: 60

Registration Number: NCT05306431

Locations: 🇵🇰
Hira Danish, Karachi, Sindh, Pakistan

Treatment of Young Permanent Teeth With Different Adjuvant Approaches

Not Applicable

Completed

Conditions: Necrotic Pulp
Periodontitis, Apical
Treatment

Interventions: Device: Laser-device group
Drug: Essential Oil
Drug: Sodium hypochlorite group

First Posted Date: 2022-03-22

Last Posted Date: 2022-03-22

Lead Sponsor: University of Belgrade

Target Recruit Count: 40

Registration Number: NCT05291195

Locations: 🇷🇸
School of Dental Medicine, University of Belgrade, Belgrade, Serbia

Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Phase 2

Conditions: Necrotic Pulp

Interventions: Dietary Supplement: Propolis nanoparticles extract solution
Drug: sodium hypochlorite

First Posted Date: 2021-12-07

Last Posted Date: 2021-12-07

Lead Sponsor: Cairo University

Target Recruit Count: 44

Registration Number: NCT05146713

The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral Load

Phase 4

Completed

Conditions: Mouthwashes
SARS-CoV-2
Viral Load
Polymerase Chain Reaction
Coronavirus
Saliva
COVID-19
Covid19

Interventions: Drug: Distilled Water
Drug: 1.5% Hydrogen Peroxide (H2O2)
Drug: 0.1% Sodium Hypochlorite
Drug: 0.075% Cetylpyridinium Chloride (CPC)
Other: No rinse group
Drug: 1% Povidone Iodine (PVP-I)

First Posted Date: 2021-01-22

Last Posted Date: 2022-07-21

Lead Sponsor: King Abdulaziz University

Target Recruit Count: 90

Registration Number: NCT04721457

Locations: 🇸🇦
Alhamra TETAMMAN clinic (PHC), Jeddah, Saudi Arabia

Adjunctive Local Sodium Hypochlorite Gel in Non Surgical Periodontal Debridement

Not Applicable

Completed

Conditions: Periodontal Diseases

Interventions: Drug: Sodium hypochlorite gel application

First Posted Date: 2020-05-22

Last Posted Date: 2020-05-22

Lead Sponsor: University of Messina

Target Recruit Count: 40

Registration Number: NCT04399187

Locations: 🇮🇹
University of Messina, Messina, Italy

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy