Metoprolol
- Generic Name
- Metoprolol
- Brand Names
- Kapspargo, Lopressor, Lopressor Hct, Toprol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25NO3
- CAS Number
- 51384-51-1
- Unique Ingredient Identifier
- GEB06NHM23
- Background
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferre...
- Indication
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.
...
- Associated Conditions
- Angina Pectoris, Atrial Fibrillation, Hypertension, Migraine, Myocardial Infarction, Supraventricular Tachycardia (SVT), Thyroid Crisis, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.
- Conditions
- Interventions
- First Posted Date
- 2021-08-17
- Last Posted Date
- 2021-08-17
- Lead Sponsor
- Xuanwu Hospital, Beijing
- Target Recruit Count
- 584
- Registration Number
- NCT05008250
Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2020-08-07
- Last Posted Date
- 2022-06-16
- Lead Sponsor
- University of Southern Denmark
- Target Recruit Count
- 10
- Registration Number
- NCT04504045
- Locations
- 🇩🇰
University of Southern Denmark, Odense, Region Of Southern Denmark, Denmark
S-Metoprolol XR 25-50 mg Tablets vs Metoprolol Zok 50-100 mg Tablets in Hypertension Patients.
- First Posted Date
- 2020-07-07
- Last Posted Date
- 2021-12-10
- Lead Sponsor
- Neutec Ar-Ge San ve Tic A.Ş
- Target Recruit Count
- 126
- Registration Number
- NCT04457323
African American Study of Kidney Disease and Hypertension
- First Posted Date
- 2020-04-27
- Last Posted Date
- 2020-04-27
- Target Recruit Count
- 1094
- Registration Number
- NCT04364139
Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy
- First Posted Date
- 2019-10-21
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- University Hospital, Motol
- Target Recruit Count
- 22
- Registration Number
- NCT04133532
- Locations
- 🇨🇿
Motol University Hospital, Praha, Czech Republic, Czechia
Metoprolol Treatment for Cytokine Release Syndrome in Patients Treated With Chimeric Antigen Receptor T Cells
- First Posted Date
- 2019-09-10
- Last Posted Date
- 2022-04-13
- Lead Sponsor
- Chinese PLA General Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT04082910
- Locations
- 🇨🇳
Biotherapeutic Department of Chinese PLA General Hospital, Beijing, Beijing, China
Efficacy and Safety of Sotalol in Children With Arrhythmia
- First Posted Date
- 2019-03-29
- Last Posted Date
- 2019-03-29
- Lead Sponsor
- Shengjing Hospital
- Target Recruit Count
- 500
- Registration Number
- NCT03895411
- Locations
- 🇨🇳
Shenjing Hospital, Shenyang, Liaoning, China
Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blocker
- First Posted Date
- 2019-02-05
- Last Posted Date
- 2019-04-12
- Target Recruit Count
- 200
- Registration Number
- NCT03830957
- Locations
- 🇮🇷
Ahmad Amin, Tehran, Iran, Islamic Republic of
Improving Right Ventricular Function in Young Adults Born Preterm
- First Posted Date
- 2018-10-05
- Last Posted Date
- 2021-03-17
- Lead Sponsor
- University of Wisconsin, Madison
- Target Recruit Count
- 10
- Registration Number
- NCT03696758
- Locations
- 🇺🇸
University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, United States
Effect of Evolocumab on Coronary Atherosclerosis
- Conditions
- Interventions
- First Posted Date
- 2018-10-01
- Last Posted Date
- 2024-07-17
- Lead Sponsor
- Cedars-Sinai Medical Center
- Target Recruit Count
- 55
- Registration Number
- NCT03689946
- Locations
- 🇺🇸
Cedars-Sinai Medical Center, Los Angeles, California, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.