Oliceridine
- Generic Name
- Oliceridine
- Brand Names
- Olinvyk
- Drug Type
- Small Molecule
- Chemical Formula
- C22H30N2O2S
- CAS Number
- 1401028-24-7
- Unique Ingredient Identifier
- MCN858TCP0
- Background
Severe acute pain occurs through nociceptive signalling involving both ascending and descending spinal pathways, in which nerve conductance is mediated in part by the action of opioid receptors. Opioid receptors are seven-transmembrane G-protein-coupled receptors (GPCRs), of which the μ-opioid receptor subtype is predominantly targeted by and is responsible ...
- Indication
用于成人治疗严重到需要静脉注射阿片类镇痛药的急性疼痛，并且替代治疗方法不足。
- Associated Conditions
- Severe Acute Pain
- Associated Therapies
- -
Clinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General Anesthesia
- First Posted Date
- 2024-10-31
- Last Posted Date
- 2024-10-31
- Lead Sponsor
- Henan Provincial People's Hospital
- Target Recruit Count
- 150
- Registration Number
- NCT06668298
To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain
- Conditions
- Interventions
- First Posted Date
- 2024-06-13
- Last Posted Date
- 2024-06-13
- Lead Sponsor
- Yuwei Qiu
- Target Recruit Count
- 75
- Registration Number
- NCT06458400
Effect of Oliceridine Analgesia on Postoperative Nause and Vomiting
- Conditions
- Interventions
- First Posted Date
- 2024-05-13
- Last Posted Date
- 2024-10-08
- Lead Sponsor
- Peking University First Hospital
- Target Recruit Count
- 252
- Registration Number
- NCT06411665
- Locations
- 🇨🇳
Dong-Xin Wang, Beijing, China
Oliceridine in Patients With Acute Burn Injuries
- Conditions
- Interventions
- First Posted Date
- 2022-07-19
- Last Posted Date
- 2023-10-26
- Lead Sponsor
- University of Tennessee
- Target Recruit Count
- 31
- Registration Number
- NCT05465226
- Locations
- 🇺🇸
Regional One Health, Memphis, Tennessee, United States
Intravenous Oliceridine and Opioid-related Complications
- First Posted Date
- 2021-07-28
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 200
- Registration Number
- NCT04979247
- Locations
- 🇺🇸
Cleveland Clinic Fairview Hospital, Cleveland, Ohio, United States
🇺🇸Wake Forest Bapist Medical Center, Winston-Salem, North Carolina, United States
🇺🇸Cleveland Clinic Main Campus, Cleveland, Ohio, United States
Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Abdominoplasty
- First Posted Date
- 2016-06-30
- Last Posted Date
- 2020-10-23
- Lead Sponsor
- Trevena Inc.
- Target Recruit Count
- 407
- Registration Number
- NCT02820324
- Locations
- 🇺🇸
Research Site, San Antonio, Texas, United States
Study of Oliceridine (TRV130) for the Treatment of Moderate to Severe Acute Pain After Bunionectomy
- First Posted Date
- 2016-06-28
- Last Posted Date
- 2020-09-25
- Lead Sponsor
- Trevena Inc.
- Target Recruit Count
- 418
- Registration Number
- NCT02815709
- Locations
- 🇺🇸
Research Site, San Antonio, Texas, United States
🇺🇸Resarch Site, Salt Lake City, Utah, United States
Drug Development Updates
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