MedPath

Amelubant

Generic Name
Amelubant
Drug Type
Small Molecule
Chemical Formula
C33H34N2O5
CAS Number
346735-24-8
Unique Ingredient Identifier
E0018IF0K4
Indication

Investigated for use/treatment in asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and rheumatoid arthritis.

Effect of BIIL 284 BS on the Pharmacokinetics of Theophylline in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2014-10-24
Last Posted Date
2014-10-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
16
Registration Number
NCT02273440

Effect of Different Food Compositions on Bioavailability of BIIL 284 BS in Healthy Male Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
Other: low fat meal
Other: high fat meal
First Posted Date
2014-10-24
Last Posted Date
2014-10-24
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
24
Registration Number
NCT02273427

Study to Evaluate the Effect of Multiple Doses of BIIL 284 BS on the Pharmacokinetics of Prednisone in Healthy Male Subjects

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2014-10-20
Last Posted Date
2014-10-20
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
20
Registration Number
NCT02268149

Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers

Phase 1
Completed
Conditions
Hepatic Insufficiency
Interventions
First Posted Date
2014-10-16
Last Posted Date
2014-10-16
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
32
Registration Number
NCT02265627

Effect of BIIL 284 BS on Patients With Chronic Obstructive Pulmonary Disease (COPD)

Phase 2
Completed
Conditions
Pulmonary Disease, Chronic Obstructive
Interventions
Drug: Placebo
First Posted Date
2014-09-25
Last Posted Date
2014-09-26
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
53
Registration Number
NCT02249338

The Effect of BIIL 284 BS on Induced-sputum Variables in Patients With Bronchial Asthma

Phase 2
Completed
Conditions
Asthma
Interventions
Drug: Placebo
First Posted Date
2014-09-25
Last Posted Date
2014-09-26
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
38
Registration Number
NCT02249312
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