Prazosin
- Generic Name
- Prazosin
- Brand Names
- Minipress, Minizide
- Drug Type
- Small Molecule
- Chemical Formula
- C19H21N5O4
- CAS Number
- 19216-56-9
- Unique Ingredient Identifier
- XM03YJ541D
- Background
Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists.
Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares.
- Indication
This drug is indicated for the treatment of hypertension (high blood pressure). Prazosin can be given alone or given with other blood pressure-lowering drugs, including diuretics or beta-adrenergic blocking agents .
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- Associated Conditions
- Agitation, Benign Prostatic Hyperplasia (BPH), Hypertension, Raynaud's Phenomenon, Disturbed sleep/nightmares
- Associated Therapies
- -
Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)
- Conditions
- Interventions
- First Posted Date
- 2006-10-29
- Last Posted Date
- 2016-10-24
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 50
- Registration Number
- NCT00393874
- Locations
- 🇺🇸
Western Phychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees
- Conditions
- Interventions
- First Posted Date
- 2005-12-05
- Last Posted Date
- 2009-12-03
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 210
- Registration Number
- NCT00261729
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Seattle, Washington, United States
Prazosin for ETOH or Cocaine Craving
- Conditions
- Interventions
- First Posted Date
- 2005-10-17
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 8
- Registration Number
- NCT00240227
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Washington, United States
Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance
- Conditions
- Interventions
- First Posted Date
- 2005-09-20
- Last Posted Date
- 2018-07-10
- Target Recruit Count
- 59
- Registration Number
- NCT00202449
- Locations
- 🇺🇸
Madigan Army Medical Center, Fort Lewis, Washington, United States
🇺🇸Walter Reed Army Medical Center, Washington, District of Columbia, United States
Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-06-14
- Target Recruit Count
- 20
- Registration Number
- NCT00183430
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Washington, United States
Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2006-09-11
- Lead Sponsor
- Rainier Associates
- Target Recruit Count
- 20
- Registration Number
- NCT00174551
- Locations
- 🇺🇸
Fletcher B. Taylor, Tacoma, Washington, United States
Prazosin Alcohol Dependence IVR Study
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2008-02-15
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 23
- Registration Number
- NCT00167687
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Washington, United States
Alzheimer's in Long-Term Care--Treatment for Agitation
- Conditions
- Interventions
- First Posted Date
- 2005-09-12
- Last Posted Date
- 2012-08-02
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 24
- Registration Number
- NCT00161473
- Locations
- 🇺🇸
Veterans Affairs Puget Sound Health Care System, Seattle, Washington, United States
Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance
- Conditions
- First Posted Date
- 2005-04-15
- Last Posted Date
- 2009-01-21
- Lead Sponsor
- US Department of Veterans Affairs
- Registration Number
- NCT00108420
- Locations
- 🇺🇸
VA Puget Sound Health Care System, Seattle, Washington, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.