Nitroglycerin
- Generic Name
- Nitroglycerin
- Brand Names
- Gonitro, Minitran, Mylan-nitro, Nitro-bid, Nitro-dur, Nitroject, Nitrolingual, Nitromist, Nitrostat, Rectiv, Trinipatch
- Drug Type
- Small Molecule
- Chemical Formula
- C3H5N3O9
- CAS Number
- 55-63-0
- Unique Ingredient Identifier
- G59M7S0WS3
- Background
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief from chest pain. Its u...
- Indication
Sublingual nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Transdermal nitroglycerin is indicated for the prevention of angina pectoris due to coronary artery disease.
...
- Associated Conditions
- Angina Attacks, Angina Pectoris, Congestive Heart Failure (CHF), Perioperative Hypertension, Moderate to severe pain
- Associated Therapies
- -
Assessment of Biomarkers and Cardiorenal Syndrome in Acute Decompensated Heart Failure With Vasodilator Therapy
- Conditions
- Interventions
- First Posted Date
- 2009-02-12
- Last Posted Date
- 2013-08-30
- Lead Sponsor
- Western University of Health Sciences
- Target Recruit Count
- 89
- Registration Number
- NCT00842023
- Locations
- 🇺🇸
Centinela Hospital Medical Center, Inglewood, California, United States
Ocular Hemodynamic Effects of Nitrovasodilators in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2008-12-18
- Last Posted Date
- 2008-12-18
- Lead Sponsor
- Medical University of Vienna
- Target Recruit Count
- 14
- Registration Number
- NCT00810381
- Locations
- 🇦🇹
Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
Effects of Different Vasodilators on Coronary No-reflow During primAry percuTaneous Coronary intErvention in Patients With Acute Myocardial Infarction
- Conditions
- Interventions
- First Posted Date
- 2008-07-10
- Last Posted Date
- 2012-09-24
- Lead Sponsor
- Fudan University
- Target Recruit Count
- 102
- Registration Number
- NCT00712894
- Locations
- 🇨🇳
Zhongshan Hospital Fudan University, Shanghai, Shanghai, China
Intravenous Nitroglycerin for Retained Placenta Extraction: a Multicenter Study
- First Posted Date
- 2008-07-01
- Last Posted Date
- 2011-03-08
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 100
- Registration Number
- NCT00707928
- Locations
- 🇹🇭
Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand
Dose Response to Topical Glyceryl Trinitrate in Patients With Raynaud's Phenomenon
- Conditions
- Interventions
- First Posted Date
- 2008-06-18
- Last Posted Date
- 2008-12-30
- Lead Sponsor
- Procris Pharmaceuticals
- Target Recruit Count
- 10
- Registration Number
- NCT00700518
- Locations
- 🇺🇸
University of Iowa-Institute for Clinical and Translational Science, Iowa City, Iowa, United States
Paclitaxel and Carboplatin With or Without Nitroglycerin in Treating Patients With Previously Untreated Stage III or Stage IV Non-Small Cell Lung Cancer
- Conditions
- First Posted Date
- 2008-02-15
- Last Posted Date
- 2013-08-12
- Lead Sponsor
- Kyoto University
- Target Recruit Count
- 150
- Registration Number
- NCT00616031
- Locations
- 🇯🇵
Kyoto University Hospital, Kyoto, Japan
Does Thiazolidinedione Therapy Improve Endothelial Function and Preserve Renal Function
- Conditions
- Interventions
- First Posted Date
- 2008-01-04
- Last Posted Date
- 2013-03-15
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 36
- Registration Number
- NCT00586261
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
A Study of a Topical Form of Nitroglycerin and Placebo in the Treatment and Prevention of Raynaud's Phenomenon
- First Posted Date
- 2007-12-20
- Last Posted Date
- 2010-02-05
- Lead Sponsor
- MediQuest Therapeutics
- Target Recruit Count
- 200
- Registration Number
- NCT00577304
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Boston University, Boston, Massachusetts, United States
🇺🇸University of Minnesota, Minneapolis, Minnesota, United States
Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine
- First Posted Date
- 2007-10-10
- Last Posted Date
- 2008-05-29
- Lead Sponsor
- Danish Headache Center
- Target Recruit Count
- 30
- Registration Number
- NCT00541736
- Locations
- 🇩🇰
Danish Headache Center, University of Copenhagen, Faculty of Health Sciences, Department of Neurology, Glostrup Hospital, Glostrup, Copenhagen, Denmark
Effect of Strategy for Blood Pressure Control on Cerebral Oxygen Balance During Aortic Coarctation Repair: A Randomized Study
- Conditions
- Interventions
- First Posted Date
- 2007-09-26
- Last Posted Date
- 2012-07-13
- Lead Sponsor
- University Hospital, Ghent
- Target Recruit Count
- 30
- Registration Number
- NCT00535808
- Locations
- 🇧🇪
University Hospital Ghent, Ghent, Belgium
Drug Development Updates
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