Deferoxamine
- Generic Name
- Deferoxamine
- Brand Names
- Desferal
- Drug Type
- Small Molecule
- Chemical Formula
- C25H48N6O8
- CAS Number
- 70-51-9
- Unique Ingredient Identifier
- J06Y7MXW4D
- Background
Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
- Indication
Used to treat acute iron or aluminum toxicity (an excess of aluminum in the body) in certain patients. Also used in certain patients with anemia who must receive many blood transfusions.
- Associated Conditions
- Aluminum overload, Chronic Iron Overload, Chronic aluminum overload, Iron Overload
- Associated Therapies
- -
ACSL4-mediated lipid rafts prevent membrane rupture and inhibit immunogenic cell death in ...
Chemicals, cell lines, and reagents were sourced from various suppliers. Cell lines were cultured under specific conditions, and xenograft assays were conducted with approved protocols. Immunostaining, mass spectrometry, transcriptomics, and other assays were performed to analyze cell viability, lipid peroxidation, and other cellular responses. Statistical analysis was conducted using GraphPad Prism 9.3.0.
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