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Patritumab

Generic Name
Patritumab
Drug Type
Biotech
CAS Number
1262787-83-6
Unique Ingredient Identifier
86780VJI1Q
Background

Patritumab has been used in trials studying the treatment of LUNG CANCER, Solid Tumors, Neoplasms by Site, Head and Neck Neoplasms, and Non-small Cell Lung Cancer, among others.

Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer

Phase 2
Active, not recruiting
Conditions
Metastatic Breast Cancer
Advanced Breast Cancer
Interventions
First Posted Date
2021-07-16
Last Posted Date
2025-02-10
Lead Sponsor
Gustave Roussy, Cancer Campus, Grand Paris
Target Recruit Count
99
Registration Number
NCT04965766
Locations
🇫🇷

Centre Georges François Leclerc, Dijon, France

🇫🇷

CHU de Limoges, Limoges, France

🇫🇷

Institut Paoli Calmettes, Marseille, France

and more 8 locations

A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer

Phase 2
Completed
Conditions
Metastatic Breast Cancer
Locally Advanced Breast Cancer
Interventions
First Posted Date
2021-01-07
Last Posted Date
2025-05-11
Lead Sponsor
SCRI Development Innovations, LLC
Target Recruit Count
121
Registration Number
NCT04699630
Locations
🇺🇸

SCRI Oncology Partners, Nashville, Tennessee, United States

🇺🇸

Tennessee Oncology, Nashville, Tennessee, United States

🇺🇸

Seattle Cancer Care Alliance, Seattle, Washington, United States

and more 8 locations

HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Cell Lung Cancer

Phase 2
Active, not recruiting
Conditions
Non-Small Cell Lung Cancer Metastatic
Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
Interventions
First Posted Date
2020-11-06
Last Posted Date
2025-05-20
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
277
Registration Number
NCT04619004
Locations
🇰🇷

The Catholic University of Korea, Seoul St. Marys Hospital, Seoul, Korea, Republic of

🇳🇱

Netherlands Cancer Institute, Amsterdam, Netherlands

🇮🇹

Azienda Ospedaliero Universitaria di Parma, Parma, Province Of Parma, Italy

and more 115 locations

A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer

Phase 2
Terminated
Conditions
Metastatic Colorectal Cancer
Interventions
First Posted Date
2020-07-21
Last Posted Date
2025-05-18
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
40
Registration Number
NCT04479436
Locations
🇬🇧

Sarah Cannon Research Institute UK, London, United Kingdom

🇯🇵

Kindai University Hospital, Osaka, Osakasayama Shi, Japan

🇪🇸

Hospital del Mar - Institut Hospital del Mar d'Investigacions Mediques IMIM, Barcelona, Spain

and more 40 locations

Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer

Phase 1
Completed
Conditions
Metastatic Breast Cancer
Interventions
First Posted Date
2016-12-02
Last Posted Date
2024-10-30
Lead Sponsor
Daiichi Sankyo Co., Ltd.
Target Recruit Count
182
Registration Number
NCT02980341
Locations
🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Southeastern Regional Medical Center, Newnan, Georgia, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

and more 23 locations

Patritumab With Cetuximab and a Platinum Agent for Squamous Cell Carcinoma (Cancer) of the Head and Neck (SCCHN )

Phase 2
Terminated
Conditions
Head and Neck Neoplasms
Interventions
First Posted Date
2015-12-17
Last Posted Date
2019-01-07
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
87
Registration Number
NCT02633800
Locations
🇫🇷

Hopital Croix-Rousse, Lyon, France

🇵🇱

Centrum Onkologii im. Prof. Franciszka Lukaszczyka w Bydgoszczy, Bydgoszcz, Poland

🇧🇪

Institut Jules Bordet, Brussels, Belgium

and more 29 locations

Patritumab With Cetuximab and a Platinum Containing Therapy for Patients With Head and Neck Cancer

Phase 1
Completed
Conditions
Squamous Cell Carcinoma of the Head and Neck
Interventions
First Posted Date
2015-01-30
Last Posted Date
2018-09-11
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
15
Registration Number
NCT02350712
Locations
🇬🇧

University College London Hospital, London, United Kingdom

🇬🇧

The Royal Marsden Hospital, London, United Kingdom

Study of Patritumab in Combination With Erlotinib in Subjects With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC). (HER3-Lung)

Phase 3
Terminated
Conditions
Lung Cancer
Non-small Cell Lung Cancer
Interventions
First Posted Date
2014-05-08
Last Posted Date
2018-01-23
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
145
Registration Number
NCT02134015

Study to Assess Pharmacokinetics, Immunogenicity and Safety/Tolerability of Patritumab (U3-1287)

Phase 1
Completed
Conditions
Solid Tumors
Interventions
First Posted Date
2013-10-08
Last Posted Date
2014-05-14
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
17
Registration Number
NCT01957280

Phase 1b/2 Study of U3-1287 in Combination With Trastuzumab Plus Paclitaxel in Newly Diagnosed Metastatic Breast Cancer (MBC)

Phase 1
Terminated
Conditions
Metastatic Breast Cancer
Interventions
First Posted Date
2012-01-19
Last Posted Date
2017-10-18
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
29
Registration Number
NCT01512199
Locations
🇦🇷

Instituto Damic - Fundacion Rusculleda, Cordoba, Argentina

🇦🇷

Unidad de Investigación FP Clinical Pharma en Centro Medico Integral Fitz Roy, Acevedo, Ciudad Autónoma de Buenos Aires, Argentina

🇦🇷

Hospital Britanico, Buenos Aires, Argentina

and more 5 locations
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