Risedronic acid

Generic Name
Risedronic acid
Brand Names
Actonel, Atelvia
Drug Type
Small Molecule
Chemical Formula
C7H11NO7P2
CAS Number
105462-24-6
Unique Ingredient Identifier
KM2Z91756Z
Background

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease. It functions by preventing resorption of bone.

Indication

Risedronic acid is indicated for the treatment of osteoperosis in men, treatment of Paget's disease, treatment and prevention of osteoperosis in postmenopausal women, and treatment and prevention of glucocorticoid-induced osteoperosis.

Associated Conditions
Hypercalcemia of Malignancy, Osteoporosis, Paget’s Disease
Associated Therapies
-

Risedronate for the Prevention of Osteoporosis in People With Spinal Cord Injury.

Phase 3
Completed
Conditions
First Posted Date
2005-09-08
Last Posted Date
2007-11-21
Lead Sponsor
Toronto Rehabilitation Institute
Target Recruit Count
38
Registration Number
NCT00150696
Locations
🇨🇦

Hamilton Health Sciences, Chedoke Site, Hamilton, Ontario, Canada

🇨🇦

Toronto Rehab, Lyndhurst Centre, Toronto, Ontario, Canada

Risedronate for the Treatment of Osteoporosis for People With Spinal Cord Injury

Phase 3
Completed
Conditions
First Posted Date
2005-08-30
Last Posted Date
2010-10-13
Lead Sponsor
Toronto Rehabilitation Institute
Target Recruit Count
46
Registration Number
NCT00138866
Locations
🇨🇦

Toronto Rehab, Lyndhurst Centre, Toronto, Ontario, Canada

OPTAMISE: Clinical Effectiveness of Teriparatide After Alendronate or Risedronate Therapy in Osteoporotic Postmenopausal Women

Phase 4
Completed
Conditions
First Posted Date
2005-08-15
Last Posted Date
2011-01-11
Lead Sponsor
Sanofi
Target Recruit Count
290
Registration Number
NCT00130403
Locations
🇦🇺

sanofi-aventis, Australia, Cove, New South Wales, Australia

🇨🇦

sanofi-aventis, Canada, Laval, Quebec, Canada

🇧🇪

sanofi-aventis, Belgium, Diegem, Belgium

and more 4 locations

Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

First Posted Date
2005-02-15
Last Posted Date
2012-06-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
185
Registration Number
NCT00103740
Locations
🇬🇧

Novartis Investigative site, Oxford, United Kingdom

🇬🇧

Novartis Investigative Site, London, United Kingdom

Anastrozole Biphosphonate Study in Postmenopausal Women With Hormone-Receptor-Positive Early Breast Cancer

Phase 4
Completed
Conditions
Interventions
First Posted Date
2004-05-06
Last Posted Date
2011-01-26
Lead Sponsor
AstraZeneca
Target Recruit Count
237
Registration Number
NCT00082277
Locations
🇬🇧

Research Site, Luton, United Kingdom

Risedronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy for Primary Breast Cancer

First Posted Date
2003-02-06
Last Posted Date
2016-07-13
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
216
Registration Number
NCT00054418
Locations
🇺🇸

Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center, Wilkes-Barre, Pennsylvania, United States

🇺🇸

Mason District Hospital, Havana, Illinois, United States

🇺🇸

Piedmont Hospital, Atlanta, Georgia, United States

and more 192 locations

Calcium With or Without Estrogen and/or Risedronate in Preventing Osteoporosis in Patients With Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2016-12-07
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
71
Registration Number
NCT00043069
Locations
🇺🇸

Memorial Hospital, Carthage, Illinois, United States

🇺🇸

Mason District Hospital, Havana, Illinois, United States

🇺🇸

Perry Memorial Hospital, Princeton, Illinois, United States

and more 111 locations

Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

First Posted Date
2003-01-15
Last Posted Date
2012-05-15
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
172
Registration Number
NCT00051636
Locations
🇬🇧

Novartis Investigative Site, Vale of Glamorgan, United Kingdom

🇬🇧

Novartis investigative site, Pernarth, United Kingdom

🇬🇧

Novartis Investigative site, Penarth, United Kingdom

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