Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy

A Study to Test How Well Different Doses of BI 1584862 Are Tolerated by Healthy Men

First Posted Date
2023-08-23
Last Posted Date
2024-05-14
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
50
Registration Number
NCT06006598
Locations
🇩🇪

Charité Research Organisation GmbH, Berlin, Germany

A Study in Healthy Volunteers to Evaluate the Drug-Drug Interaction Potential of CCX168 With Concomitant Medications

First Posted Date
2023-08-22
Last Posted Date
2023-08-22
Lead Sponsor
Amgen
Target Recruit Count
32
Registration Number
NCT06004947
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

Efficacy and Safety of Remimazolam Compared With Midazolam During Bronchoscopy:Randomised Controlled Trial

Phase 4
Completed
Conditions
Interventions
First Posted Date
2023-08-16
Last Posted Date
2023-08-16
Lead Sponsor
Chungbuk National University Hospital
Target Recruit Count
100
Registration Number
NCT05994547
Locations
🇰🇷

Chungbuk National University Hospital, Cheongju-si, Chungcheongbuk-do, Korea, Republic of

Voxelotor CYP and Transporter Cocktail Interaction Study

First Posted Date
2023-08-08
Last Posted Date
2024-11-22
Lead Sponsor
Pfizer
Target Recruit Count
44
Registration Number
NCT05981365
Locations
🇺🇸

ICON Early Phase Services, LLC, San Antonio, Texas, United States

Remimazolam for Cataract Surgery

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2023-08-07
Last Posted Date
2024-12-13
Lead Sponsor
University of California, Los Angeles
Target Recruit Count
120
Registration Number
NCT05980117
Locations
🇺🇸

Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California, United States

A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failure

First Posted Date
2023-07-19
Last Posted Date
2024-04-04
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
13
Registration Number
NCT05952089
Locations
🇺🇸

Research Integrity LLC, Owensboro, Kentucky, United States

🇺🇸

Holy Cross Hospital, Fort Lauderdale, Florida, United States

🇺🇸

Sinai Hospital Of Baltimore, Baltimore, Maryland, United States

and more 2 locations

DDI Study of Single Oral Dose of Acoziborole With Sequential Co-administration of Midazolam and Dextromethorphan

First Posted Date
2023-07-17
Last Posted Date
2023-07-17
Lead Sponsor
Drugs for Neglected Diseases
Target Recruit Count
20
Registration Number
NCT05947604
Locations
🇲🇾

Clinical Research Center (CRC) Ampang Hospital, Kuala Lumpur, Malaysia

Ketamine and Midazolam Infusions for CRPS: Feasibility Study

First Posted Date
2023-07-14
Last Posted Date
2024-11-22
Lead Sponsor
Stanford University
Registration Number
NCT05945147
Locations
🇺🇸

Stanford University, Stanford, California, United States

A Study to Assess the Effect of BMS-986419 on the Single Dose Drug Levels of Probe Substrates in Healthy Participants

First Posted Date
2023-07-06
Last Posted Date
2023-10-30
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
22
Registration Number
NCT05932277
Locations
🇺🇸

ICON Lenexa, Lenexa, Kansas, United States

Clinical Study of Oral Midazolam Combined With Esketamine Administered Intranasally for Pediatric Preoperative Sedation

First Posted Date
2023-06-29
Last Posted Date
2023-06-29
Lead Sponsor
Second Affiliated Hospital of Wenzhou Medical University
Target Recruit Count
126
Registration Number
NCT05925283
Locations
🇨🇳

The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China

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