Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy

AZD1981 Midazolam CYP4503A Induction Study

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-03-11
Last Posted Date
2009-04-10
Lead Sponsor
AstraZeneca
Target Recruit Count
28
Registration Number
NCT00859352
Locations
🇸🇪

Research Site, Uppsala, Sweden

Study Evaluating The Co-Administration Of Moxidectin And Midazolam In Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-03-05
Last Posted Date
2010-09-16
Lead Sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Target Recruit Count
38
Registration Number
NCT00856362

Sedation and Pain (The Effect of IV Sedation on Pain Perception)

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2009-03-02
Last Posted Date
2014-06-26
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
86
Registration Number
NCT00853333
Locations
🇺🇸

University of Alabama at Birmingham, Birmingham, Alabama, United States

Bronchoscopy and Bispectral Index (BIS) - Guided Sedation

Phase 4
Completed
Conditions
Interventions
First Posted Date
2009-02-09
Last Posted Date
2009-02-09
Lead Sponsor
University Hospital, Geneva
Target Recruit Count
84
Registration Number
NCT00839371
Locations
🇨🇭

Centre Valaisan de Pneumologie, Montana, Switzerland

Effect of Multiple Doses of AZD6280 on the Pharmacokinetics of Midazolam (CYP3A4) and Caffeine (CYP1A2)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-01-16
Last Posted Date
2009-07-31
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT00824057
Locations
🇬🇧

Research Site, London, United Kingdom

The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers

Phase 4
Conditions
Interventions
First Posted Date
2008-12-19
Last Posted Date
2009-11-18
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT00811837
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services

First Posted Date
2008-11-17
Last Posted Date
2008-11-17
Lead Sponsor
Sahlgrenska University Hospital, Sweden
Target Recruit Count
2800
Registration Number
NCT00792181

Determine the Effect of Multiple Doses of AZD7325, CYP Study

First Posted Date
2008-11-13
Last Posted Date
2008-11-13
Lead Sponsor
AstraZeneca
Target Recruit Count
24
Registration Number
NCT00790114

The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers

Phase 4
Conditions
Interventions
First Posted Date
2008-11-11
Last Posted Date
2009-05-21
Lead Sponsor
Medical University of Vienna
Target Recruit Count
24
Registration Number
NCT00789386
Locations
🇦🇹

Department of Anaesthesia, Medical University of Vienna, Vienna, Austria

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