Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy

Optimization of IV Ketamine for Treatment Resistant Depression

First Posted Date
2008-10-08
Last Posted Date
2014-01-31
Lead Sponsor
Baylor College of Medicine
Target Recruit Count
73
Registration Number
NCT00768430
Locations
🇺🇸

Michael E. Dabakey VA Medical Center & Baylor College of Medicine, Houston, Texas, United States

🇺🇸

Mount Sinai School of Medicine, New York, New York, United States

Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD)

First Posted Date
2008-09-09
Last Posted Date
2018-02-14
Lead Sponsor
Dennis Charney
Target Recruit Count
41
Registration Number
NCT00749203
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Dexmedetomidine Versus Midazolam for Facilitating Extubation

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-09-01
Last Posted Date
2016-09-28
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
23
Registration Number
NCT00744380
Locations
🇺🇸

University of Colorado Hospital, Aurora, Colorado, United States

Ultrasound-Guided Axillary or Infraclavicular Nerve Block for Upper Limb Surgery

First Posted Date
2008-07-29
Last Posted Date
2009-07-15
Lead Sponsor
University of Parma
Target Recruit Count
52
Registration Number
NCT00724035
Locations
🇮🇹

University Hospital / Azienda Ospedaliero-Universitaria, Parma, PR, Italy

Drug Interaction Study to Asses Multiple Doses of ZD4054 (Zibotentan)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-07-03
Last Posted Date
2010-09-28
Lead Sponsor
AstraZeneca
Target Recruit Count
12
Registration Number
NCT00709553
Locations
🇩🇪

Research Site, Berlin, Germany

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-06-04
Last Posted Date
2010-12-10
Lead Sponsor
AstraZeneca
Target Recruit Count
60
Registration Number
NCT00689780
Locations
🇸🇪

Research Site, Upssala, Sweden

The Effect of Sedation on Eye Movements

First Posted Date
2008-03-28
Last Posted Date
2017-05-19
Lead Sponsor
University of Alabama at Birmingham
Target Recruit Count
65
Registration Number
NCT00646646
Locations
🇺🇸

General Clinical Research Center, Birmingham, Alabama, United States

Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)

First Posted Date
2008-03-24
Last Posted Date
2011-11-22
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
10
Registration Number
NCT00641563
Locations
🇨🇭

Departement of Intensive Care Medicine - University Hospital Bern - Inselspital, Bern, Switzerland

Clonidine Versus Midazolam for Premedication

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2008-03-19
Last Posted Date
2008-03-19
Lead Sponsor
University Hospital Schleswig-Holstein
Target Recruit Count
60
Registration Number
NCT00638729
Locations
🇩🇪

Department of Anaesthesiology and Intensive Care Medicine, University of Schleswig-Holstein Campus Kiel, Kiel, Germany

Clinical Trial of Oral Midazolam in Pediatric Endoscopy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-03-14
Last Posted Date
2008-04-11
Lead Sponsor
Tabriz University
Target Recruit Count
50
Registration Number
NCT00636428
Locations
🇮🇷

Liver &Gastrointestinal Research center of tabriz medical university, Tabriz, East Azarbijan, Iran, Islamic Republic of

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