Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-05-09
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- University of Novi Sad
- Target Recruit Count
- 200
- Registration Number
- NCT05849597
- Locations
- 🇷🇸
Institute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica, Serbia
Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery
- Conditions
- Interventions
- First Posted Date
- 2023-05-06
- Last Posted Date
- 2024-04-09
- Lead Sponsor
- Xijing Hospital
- Target Recruit Count
- 280
- Registration Number
- NCT05843383
- Locations
- 🇨🇳
Xijing Hospital, Xi'an, Shaanxi, China
Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
- Conditions
- Interventions
- First Posted Date
- 2023-04-28
- Last Posted Date
- 2023-04-28
- Lead Sponsor
- Samsung Medical Center
- Target Recruit Count
- 60
- Registration Number
- NCT05835713
Comparison of Postoperative Recovery of Sevoflurane and Propofol After Transsphenoidal Surgery
- First Posted Date
- 2023-04-21
- Last Posted Date
- 2024-05-01
- Lead Sponsor
- Peking Union Medical College Hospital
- Target Recruit Count
- 252
- Registration Number
- NCT05822817
- Locations
- 🇨🇳
Peking Union Medical College Hospital, Beijing, Beijing, China
The Safety of Etomidate - Propofol Mixture vs Propofol in Total Intravenous Anesthesia During Abdominal Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-04-12
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Ailin Luo
- Target Recruit Count
- 468
- Registration Number
- NCT05810363
- Locations
- 🇨🇳
Tongji hospital, Wuhan, China
Continuous Infusion of Remidazolam for Colonoscopic Polypectomy in Elderly Patients
- First Posted Date
- 2023-04-06
- Last Posted Date
- 2024-08-13
- Lead Sponsor
- Tongji Hospital
- Target Recruit Count
- 114
- Registration Number
- NCT05801757
- Locations
- 🇨🇳
Tongji Hospital, Wuhan, Hubei, China
Effect of Midazolam Bolus on Eleveld and Schnider TCI (Target Controlled Infusion) Models
- First Posted Date
- 2023-04-05
- Last Posted Date
- 2023-10-19
- Lead Sponsor
- University of Padova
- Target Recruit Count
- 40
- Registration Number
- NCT05800288
- Locations
- 🇮🇹
ULSS2, Treviso, Italy
Development of a Pharmacodynamic Model for Propofol in Older Adults
- First Posted Date
- 2023-03-30
- Last Posted Date
- 2024-06-04
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 60
- Registration Number
- NCT05790720
- Locations
- 🇨🇱
Pontificia Universidad Católica de Chile, Santiago, Región Metropolitana, Chile
Evaluation of Equivalent Minimum Alveolar Concentration (eMAC) During Propofol/Remifentanil Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2023-03-29
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Zhang Haopeng
- Target Recruit Count
- 62
- Registration Number
- NCT05789992
- Locations
- 🇨🇳
Xijing Hospital, Xian, Shaanxi, China
Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2023-03-24
- Last Posted Date
- 2023-03-24
- Lead Sponsor
- Tianjin First Central Hospital
- Target Recruit Count
- 165
- Registration Number
- NCT05783518
- Locations
- 🇨🇳
TianjinFCH, Tianjin, Tianjin, China
Drug Development Updates
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