Iodixanol
- Generic Name
- Iodixanol
- Brand Names
- Visipaque, Visipaque 270, Visipaque 320
- Drug Type
- Small Molecule
- Chemical Formula
- C35H44I6N6O15
- CAS Number
- 92339-11-2
- Unique Ingredient Identifier
- HW8W27HTXX
- Background
Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
- Indication
Iodixanol is a contrast agent during coronary angiography.
Isovue in Peripheral Digital Subtraction Angiography (DSA)
- Conditions
- Peripheral Arterial Occlusive Disease
- Interventions
- First Posted Date
- 2010-02-25
- Last Posted Date
- 2013-05-30
- Lead Sponsor
- Bracco Diagnostics, Inc
- Target Recruit Count
- 174
- Registration Number
- NCT01075217
- Locations
- 🇺🇸
Bracco Diagnostics, Princeton, New Jersey, United States
Single Dose Safety, Tolerance and Pharmacokinetic Study in Healthy Volunteers Undergoing Contrast-enhanced Abdominal Computed Tomography (CT)
- Conditions
- Healthy
- Interventions
- Drug: GE-145 (AN113111) Injection
- First Posted Date
- 2009-10-30
- Last Posted Date
- 2012-04-05
- Lead Sponsor
- GE Healthcare
- Target Recruit Count
- 50
- Registration Number
- NCT01004770
- Locations
- 🇺🇸
GE Healthcare, Princeton, New Jersey, United States
A Safety Comparison of Iopromide and Iodixanol in Renal Impaired Patients
- Conditions
- Kidney Failure, Chronic
- Interventions
- First Posted Date
- 2009-06-23
- Last Posted Date
- 2011-06-27
- Lead Sponsor
- Chinese PLA General Hospital
- Target Recruit Count
- 592
- Registration Number
- NCT00926562
- Locations
- 🇨🇳
Tianjin Chest Hospital, Tianjin, Tianjin, China
🇨🇳Henan Provincial People's Hospital, Zhengzhou, Henan, China
🇨🇳China-Japan Union Hospital of Jilin University, Changchun, Jilin, China
Comparison Between Iso-Osmolar and Ipo-Osmolar Contrast Agents in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary Percutaneous Coronary Intervention (PCI)
- Conditions
- Contrast Induced NephropathyAcute Myocardial Infarction
- Interventions
- First Posted Date
- 2009-01-23
- Last Posted Date
- 2010-11-16
- Lead Sponsor
- Ospedale San Donato
- Target Recruit Count
- 432
- Registration Number
- NCT00827788
- Locations
- 🇮🇹
Cardiovascular Department, Ospedale S.Donato, Arezzo, AR, Italy
Intra-discal Steroid Injection for MODIC I Discopathy
- Conditions
- Back Pain Lower Back Chronic
- Interventions
- Drug: Placebo comparator
- First Posted Date
- 2008-12-09
- Last Posted Date
- 2017-08-14
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 137
- Registration Number
- NCT00804531
- Locations
- 🇫🇷
Hôpital Cochin, Paris, France
Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography
- Conditions
- Renal Impairment
- Interventions
- First Posted Date
- 2008-11-19
- Last Posted Date
- 2019-03-06
- Lead Sponsor
- Guerbet
- Target Recruit Count
- 6
- Registration Number
- NCT00793182
- Locations
- 🇺🇸
Albert Einstein Medical Center, Philadelphia, Pennsylvania, United States
🇺🇸UAB Hospital, Birmingham, Alabama, United States
🇺🇸Providence Hospital, Washington, District of Columbia, United States
Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients
- Conditions
- Chronic Renal ImpairmentDiabetes Mellitus
- Interventions
- First Posted Date
- 2008-10-31
- Last Posted Date
- 2012-01-26
- Lead Sponsor
- Bracco Diagnostics, Inc
- Target Recruit Count
- 23
- Registration Number
- NCT00782639
- Locations
- 🇺🇸
Bracco Diagnostics Inc., Princeton, New Jersey, United States
Pilot Study to Compare ISOVUE®-250 and VISIPAQUE™ 270 for Motion Artifact and Pain in Peripheral DSA
- Conditions
- Peripheral Arterial Occlusive Disease
- Interventions
- First Posted Date
- 2008-08-22
- Last Posted Date
- 2011-05-09
- Lead Sponsor
- Bracco Diagnostics, Inc
- Target Recruit Count
- 33
- Registration Number
- NCT00740207
Mechanisms for the Effect of Acetylcysteine on Renal Function After Exposure to Radiographic Contrast Material
- Conditions
- Radiocontrast-induced Nephropathy
- Interventions
- First Posted Date
- 2007-11-14
- Last Posted Date
- 2015-06-08
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 90
- Registration Number
- NCT00558142
- Locations
- 🇬🇧
Clinical Research Facility, Royal Infirmary Edinburgh, Edinburgh, Midlothian, United Kingdom
Iodixanol vs. Iomeprol to Prevent Contrast-Induced Nephropathy After Coronary Intervention (CONTRAST)
- Conditions
- Renal Insufficiency, ChronicCoronary ArteriosclerosisAngioplasty, Transluminal, Percutaneous Coronary
- Interventions
- First Posted Date
- 2006-10-20
- Last Posted Date
- 2010-03-15
- Lead Sponsor
- Deutsches Herzzentrum Muenchen
- Target Recruit Count
- 324
- Registration Number
- NCT00390585
- Locations
- 🇩🇪
1. Medizinische Klinik, Klinikum rechts der Isar, Muenchen, Germany
🇩🇪Deutsches Herzzentrum Muenchen, Munich, Germany
Drug Development Updates
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