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Doxercalciferol

Generic Name
Doxercalciferol
Brand Names
Hectorol
Drug Type
Small Molecule
Chemical Formula
C28H44O2
CAS Number
54573-75-0
Unique Ingredient Identifier
3DIZ9LF5Y9

Overview

Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured by Catalent Pharma Solutions, Inc.

Background

Doxercalciferol is a synthetic vitamin D2 analog that undergoes metabolic activation in vivo to form 1α,25-dihydroxyvitamin D2 (1α,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease. Doxercalciferol is marketed under the brand name Hectoral by Genzyme Corporation, and is manufactured by Catalent Pharma Solutions, Inc.

Indication

Doxercalciferol is indicated for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as for the treatment of secondary hyperparathyroidism in patients with Stage 3 or Stage 4 chronic kidney disease.

Associated Conditions

  • Secondary Hyperparathyroidism (SHPT)

FDA Approved Products

Hectorol
Manufacturer:Genzyme Corporation
Route:INTRAVENOUS
Strength:2 ug in 1 mL
Approved: 2023/04/27
NDC:58468-0126
Doxercalciferol
Manufacturer:Eugia US LLC
Route:INTRAVENOUS
Strength:4 ug in 2 mL
Approved: 2024/02/08
NDC:55150-359
Doxercalciferol
Manufacturer:Alembic Pharmaceuticals Inc.
Route:INTRAVENOUS
Strength:4 ug in 2 mL
Approved: 2023/06/20
NDC:62332-690
Doxercalciferol
Manufacturer:Chartwell RX, LLC
Route:ORAL
Strength:0.5 ug in 1 1
Approved: 2023/01/30
NDC:62135-450
Doxercalciferol
Manufacturer:West-Ward Pharmaceuticals Corp.
Route:ORAL
Strength:2.5 ug in 1 1
Approved: 2017/04/25
NDC:0054-0339

Singapore Approved Products

No Singapore products found for this drug

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