MedPath

Sodium hydroxide

Generic Name
Sodium hydroxide
Drug Type
Small Molecule
Chemical Formula
HNaO
CAS Number
1310-73-2
Unique Ingredient Identifier
55X04QC32I

Overview

Sodium hydroxide is also known as lye or soda , or caustic soda . At room temperature, sodium hydroxide is a white crystalline odorless solid that absorbs moisture from the air. It is a synthetically manufactured substance. When dissolved in water or neutralized with acid it releases substantial amounts of heat, which may prove sufficient to ignite combustible materials. Sodium hydroxide is highly corrosive . Sodium hydroxide is generally used as a solid or a diluted in a 50% solution. This chemical is used to manufacture soaps, rayon, paper, explosives, dyestuffs, and petroleum products . It is also used in processing cotton fabric, laundering and bleaching, metal cleaning and processing, oxide coating, electroplating, and electrolytic extracting. It is commonly found in commercial drain/ oven cleaners . According to the the FDA, sodium hydroxide is considered a direct food recognized as safe, where it serves as a pH control agent and follows good manufacturing guidelines . Interestingly, sodium hydroxide has been studied for its use in the treatment of prion disease (as occurs in mad cow disease and kuru). The use of this compound has been shown to effectively reduce prion levels in an in vitro inactivation assay .

Indication

Used to destroy or kill the nail matrix (matrixectomies) .

Associated Conditions

  • Dehydration Hypertonic
  • Isotonic Dehydration

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor

No clinical trials found

No clinical trials found for this drug

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Cantrell Drug Company
52533-174
EPIDURAL
N/A
1/13/2015
Cantrell Drug Company
52533-105
INTRAVENOUS
N/A
12/11/2014
Cantrell Drug Company
52533-166
INTRAVENOUS
N/A
3/6/2015
Novo Nordisk
0169-3205
SUBCUTANEOUS
N/A
6/21/2023
Mylan Institutional LLC
67457-585
SUBCUTANEOUS
N/A
8/15/2020
Cantrell Drug Company
52533-211
INTRAVENOUS
N/A
12/24/2014
Cantrell Drug Company
52533-025
INTRAVENOUS
N/A
8/13/2014
Mylan Institutional LLC
67457-593
SUBCUTANEOUS
N/A
6/8/2020
Cantrell Drug Company
52533-001
INTRAVENOUS
N/A
1/14/2016
Bryant Ranch Prepack
63629-8744
INTRAMUSCULAR
N/A
8/24/2021

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION
SIN15411P
INFUSION, SOLUTION
0.360g/1000ml
1/23/2018
NUTRIFLEX® OMEGA SPECIAL EMULSION FOR INFUSION
SIN15469P
INJECTION, EMULSION
1.171g/1000ml
4/23/2018
NUTRIFLEX® OMEGA SPECIAL B. BRAUN EMULSION FOR INFUSION
SIN16734P
INJECTION, EMULSION
1.171g/1000ml
3/7/2023
COMPOUND SODIUM LACTATE INTRAVENOUS INFUSION BP
SIN06281P
INJECTION
0.115 g/100 ml
6/11/1991
NUTRIFLEX® OMEGA PLUS EMULSION FOR INFUSION
SIN15468P
INJECTION, EMULSION
0.781g/1000ml
4/23/2018

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
NUTRIFLEX OMEGA SPECIAL EMULSION FOR INFUSION
N/A
N/A
N/A
1/11/2012
NUTRIFLEX OMEGA PLUS EMULSION FOR INFUSION
N/A
N/A
N/A
1/11/2012

TGA Drug Approvals

Approved Product
ARTG ID
Sponsor
Registration Type
Status
Registration Date
ATROPINE JUNO atropine sulfate monohydrate 600 microgram/1mL injection BP ampoule
374285
Medicine
A
7/5/2022

Health Canada Drug Approvals

Approved Product
Company
DIN
Dosage Form
Strength
Market Date
VAMIN N
02065665
Solution - Intravenous
200 MG / 100 ML
12/31/1995

CIMA AEMPS Drug Approvals

Approved Product
Company
Registration Number
Pharmaceutical Form
Prescription Type
Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product
Company
License Number
Dosage Form
Strength
Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product
Company
Registration Number
Dosage Form
Strength
Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name
MA Holder
MA Number
Pharmaceutical Form
Active Ingredient
Authorization Date
No UK EMC drug information found for this drug.

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