Norfloxacin

Generic Name
Norfloxacin
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C16H18FN3O3
CAS Number
70458-96-7
Unique Ingredient Identifier
N0F8P22L1P
Background

A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.

Indication

For the treatment of urinary tract infection

Associated Conditions
Cystitis, Gonococcal cervicitis, Infectious diarrhea, Pyelitis, Pyelonephritis, Spontaneous Bacterial Peritonitis (SBP), Traveler's Diarrhea, Urethritis gonococcal
Associated Therapies
-

Efficacy of Rifaximin vs Norfloxacin for Secondary Prophylaxis of SBP (NORRIF Trial)

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-01-10
Last Posted Date
2024-01-10
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
280
Registration Number
NCT06199843
Locations
🇮🇳

Dr Jaya Benjamin, New Delhi, Delhi, India

Nitazoxanide in Prevention of Secondary Spontaneous Peritonitis

First Posted Date
2021-02-10
Last Posted Date
2021-02-10
Lead Sponsor
Tanta University
Target Recruit Count
60
Registration Number
NCT04746937

Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

First Posted Date
2019-11-13
Last Posted Date
2019-11-13
Lead Sponsor
Tanta University
Target Recruit Count
80
Registration Number
NCT04161768
Locations
🇪🇬

Sherief Abd-Elsalam, Tanta, Egypt

Rifaximin Versus Norfloxacin in Spontaneous Bacterial Peritonitis

First Posted Date
2019-11-12
Last Posted Date
2021-02-16
Lead Sponsor
Ospedali Riuniti di Foggia
Target Recruit Count
322
Registration Number
NCT04159870
Locations
🇮🇹

Ospedali Riuniti Foggia, Foggia, Italy

Comparison of the Efficacy of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Norfloxacin in Secondary Prophylaxis for Spontaneous Bacterial Peritonitis

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2018-10-11
Last Posted Date
2019-10-24
Lead Sponsor
Institute of Liver and Biliary Sciences, India
Target Recruit Count
120
Registration Number
NCT03702426
Locations
🇮🇳

Institute of Liver & Biliary Sciences, New Delhi, Delhi, India

Comparative Study of Rifaximin Versus Norfloxacin in the Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

First Posted Date
2014-04-22
Last Posted Date
2018-01-09
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
100
Registration Number
NCT02120196
Locations
🇪🇬

Tanta university hospital, Tanta, Egypt

Norfloxacin Versus Ciprofloxacin for Spontaneous Bacterial Peritonitis (SBP) Prevention

First Posted Date
2012-03-02
Last Posted Date
2016-12-28
Lead Sponsor
Korea University
Target Recruit Count
124
Registration Number
NCT01542801
Locations
🇰🇷

Korea University Ansan Hospital, Ansan, Gyeonggi-do, Korea, Republic of

🇰🇷

Kyungpuk National University Hospital, Daegu, Korea, Republic of

🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

and more 4 locations

Comparison in the Treatment of Acute Cystitis Using Cephalosporin and Norfloxacin (CECI)

Phase 3
Withdrawn
Conditions
Interventions
First Posted Date
2012-02-06
Last Posted Date
2015-07-27
Lead Sponsor
Eurofarma Laboratorios S.A.
Registration Number
NCT01527019

Symptomatic Therapy of Uncomplicated Lower Urinary Tract Infections in the Ambulatory Setting.

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2009-12-25
Last Posted Date
2015-07-09
Lead Sponsor
Insel Gruppe AG, University Hospital Bern
Target Recruit Count
253
Registration Number
NCT01039545
Locations
🇨🇭

Institute for Infectious Diseases, University of Berne, Berne, Switzerland

Norfloxacin Therapy for Patients With Cirrhosis and Severe Liver Failure

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2009-12-23
Last Posted Date
2015-12-09
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
291
Registration Number
NCT01037959
Locations
🇫🇷

Assisatnce publique Hoptitaux de Paris, Clichy, France

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