Loxapine

Generic Name
Loxapine
Brand Names
Adasuve, Xylac
Drug Type
Small Molecule
Chemical Formula
C18H18ClN3O
CAS Number
1977-10-2
Unique Ingredient Identifier
LER583670J
Background

An antipsychotic agent used in schizophrenia. [PubChem]

Indication

For the management of the manifestations of psychotic disorders such as schizophrenia

Associated Conditions
Acute Agitation, Schizophrenia
Associated Therapies
-

Inhaled Loxapine vs Intramuscular (IM) Haloperidol + Lorazepam for Agitation

First Posted Date
2017-04-12
Last Posted Date
2018-06-11
Lead Sponsor
University of Arkansas
Target Recruit Count
2
Registration Number
NCT03110900
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Tolerability and Analgesic Efficacy of Loxapine in Patients With Refractory, Chemotherapy-induced Neuropathic Pain

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2016-07-01
Last Posted Date
2022-07-01
Lead Sponsor
University of Witten/Herdecke
Target Recruit Count
4
Registration Number
NCT02820519
Locations
🇩🇪

HELIOS Clinic Wuppertal, Wuppertal, NRW, Germany

Loxapine in the Management of Restlessness During Mechanical Ventilation Weaning

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-09-02
Last Posted Date
2014-07-18
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
100
Registration Number
NCT01193816
Locations
🇫🇷

Hôpital Louis Mourier, Colombes, France

Randomized Double-blind Trial of Midazolam and Loxapine in Agitated Patients

First Posted Date
2006-02-10
Last Posted Date
2015-03-11
Lead Sponsor
University Hospital, Rouen
Target Recruit Count
120
Registration Number
NCT00290082
Locations
🇫🇷

Emergency Department, St Etienne, France

🇫🇷

Emergecy department, Argenteuil, France

Loxapine and Weaning From Ventilator

Not Applicable
Completed
Conditions
First Posted Date
2005-07-22
Last Posted Date
2007-07-23
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
9
Registration Number
NCT00122733
Locations
🇫🇷

Service de Réanimation, Hopital Louis Mourier, Colombes, France

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