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Emtricitabine and tenofovir disoproxil fumarate

Generic Name
Emtricitabine and tenofovir disoproxil fumarate
Indication

适用于与其他抗逆转录病毒药物联用,治疗成人和12岁(含)以上儿童的 HIV-1感染。

SCOPE: Strategies to Combine PrEP With Prevention Efforts

Not Applicable
Withdrawn
Conditions
HIV
Interventions
First Posted Date
2013-04-16
Last Posted Date
2013-07-15
Lead Sponsor
FHI 360
Registration Number
NCT01832571
Locations
🇰🇪

Sex Workers Outreach Programme (SWOP), Nairobi, Kenya

🇰🇪

Family Health Options Kenya, Eldoret, Kenya

A Pilot Study on Raltegravir, Tenofovir and Emtricitabine for Peri-exposure Prophylaxis for HIV Infection

Phase 3
Conditions
Infection
HIV
Interventions
First Posted Date
2012-10-02
Last Posted Date
2012-10-02
Lead Sponsor
Projeto Praça Onze
Target Recruit Count
65
Registration Number
NCT01697046
Locations
🇧🇷

Monica Barbosa de Souza, Rio de Janeiro, RJ, Brazil

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure

Phase 4
Completed
Conditions
HIV-1 Infection
Interventions
Drug: Second line ART regimens - based on a boosted protease inhibitor (bPI) plus two nucleoside analogues (NRTIs)
Drug: Study provided drugs according to patient resistance profile (DRV, ETR, RTV, FTC/TDF) + any in country available drug as applicable & available
Other: SOC adherence versus SOC+CPI adherence
First Posted Date
2012-07-16
Last Posted Date
2019-03-15
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
545
Registration Number
NCT01641367
Locations
🇧🇷

Hospital Nossa Senhora da Conceicao CRS (12201), Porto Alegre, RS, Brazil

🇧🇷

Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro, Brazil

🇮🇳

Chennai Antiviral Research and Treatment (CART) CRS (11701), Chennai, Taramani, India

and more 16 locations

Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected

Phase 1
Completed
Conditions
HIV-1 Infection
Pf Subclinical Parasitemia
Interventions
First Posted Date
2012-07-03
Last Posted Date
2019-08-06
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
52
Registration Number
NCT01632891
Locations
🇰🇪

AMPATH at Moi Univ. Teaching Hosp. Eldoret CRS (12601), Eldoret, Kenya

🇰🇪

Walter Reed Project - Kenya Med. Research Institute Kericho CRS (12501), Kericho, Kenya

🇲🇼

College of Med. JHU CRS (30301), Blantyre, Malawi

and more 2 locations

On Demand Antiretroviral Pre-exposure Prophylaxis for HIV Infection in Men Who Have Sex With Men

Phase 3
Completed
Conditions
HIV Infection
Interventions
Drug: Placebo
First Posted Date
2011-11-17
Last Posted Date
2017-05-11
Lead Sponsor
ANRS, Emerging Infectious Diseases
Target Recruit Count
400
Registration Number
NCT01473472
Locations
🇫🇷

CHU Hôtel Dieu, Nantes, France

🇫🇷

Hôpital de l'Archet, Nice, France

🇫🇷

Hôpital Gustave Dron, Tourcoing, France

and more 4 locations

Trial To Assess The Lipid-Lowering Effect Of Adding Tenofovir/Emtricitabine Co-Formulation Vs Placebo To Hiv-1-Infected Subjects With Dyslipidemia And Sustained Viral Load Suppression Under Monotherapy With Ritonavir-Boosted Protease Inhibitors

Phase 4
Completed
Conditions
HIV
Dyslipidemia
Interventions
First Posted Date
2011-10-25
Last Posted Date
2014-06-19
Lead Sponsor
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la Promoción de la Salud y la Ciencia
Target Recruit Count
48
Registration Number
NCT01458977
Locations
🇪🇸

Hospital de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain

🇪🇸

Hospital Valle Hebrón, Barcelona, Spain

🇪🇸

Germans Trias i Pujol Hospital, Badalona, Barcelona, Spain

A Key Link for Transmission Prevention

Not Applicable
Completed
Conditions
HIV
Interventions
Behavioral: Standard HIV prevention messages
First Posted Date
2011-10-12
Last Posted Date
2018-04-19
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
46
Registration Number
NCT01450189
Locations
🇲🇼

Lighthouse Trust, Kamuzu Central Hospital, Lilongwe, Malawi

🇲🇼

UNC Project, Lilongwe, Malawi

REMEMBER: Reducing Early Mortality & Morbidity by Empiric Tuberculosis (TB) Treatment

Phase 4
Completed
Conditions
HIV Infection
Interventions
Drug: Rifampin/isoniazid/pyrazinamide/ethambutol FDC
Drug: Rifampin/isoniazid FDC
First Posted Date
2011-06-27
Last Posted Date
2024-10-14
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
851
Registration Number
NCT01380080
Locations
🇮🇳

BJ Medical College CRS, Pune, Maharashtra, India

🇮🇳

YRG CARE Medical Ctr., VHS Chennai CRS, Rajiv Gandhi Salai Taramani, Chennai, India

🇭🇹

GHESKIO Institute of Infectious Diseases and Reproductive Health (GHESKIO - IMIS) CRS, Port Au Prince, Haiti

and more 15 locations

Study of Options for Second-Line Effective Combination Therapy (SELECT)

Phase 3
Completed
Conditions
HIV-1 Infection
Interventions
First Posted Date
2011-05-12
Last Posted Date
2021-08-05
Lead Sponsor
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Target Recruit Count
515
Registration Number
NCT01352715
Locations
🇧🇷

Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro, Brazil

🇲🇼

University of North Carolina Lilongwe CRS (12001), Lilongwe, Malawi

🇿🇦

Soweto ACTG CRS (12301), Johannesburg, South Africa

and more 13 locations
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