Emtricitabine and tenofovir disoproxil fumarate

Generic Name: Emtricitabine and tenofovir disoproxil fumarate

Indication: 适用于与其他抗逆转录病毒药物联用，治疗成人和12岁（含）以上儿童的 HIV-1感染。

Clinical Trials

PrEPsmart 2-1-1 Pilot

Phase 2

Recruiting

Conditions: HIV-1-infection

Interventions: Device: PrEPsmart mobile app
Drug: Truvada

First Posted Date: 2024-10-08

Last Posted Date: 2024-10-08

Lead Sponsor: Public Health Foundation Enterprises, Inc.

Target Recruit Count: 60

Registration Number: NCT06631365

Locations: 🇺🇸
Bridge HIV, San Francisco Department of Public Health, San Francisco, California, United States

PrEPared-RN, CAN Nurse-Led Management of High-risk Patients for Pre-Exposure Prophylaxis (PrEP)

Recruiting

Conditions: Pre-Exposure Prophylaxis (PrEP)
Hiv Prevention

First Posted Date: 2023-09-11

Last Posted Date: 2023-09-11

Lead Sponsor: CAN Community Health

Target Recruit Count: 210

Registration Number: NCT06030557

Locations: 🇺🇸
CAN Community Health, Plantation, Florida, United States

Effects of Antiviral Therapies on Epstein-Barr Virus Replication

Phase 2

Conditions: Multiple Sclerosis

Interventions: Drug: Truvada (tenofovir/emtricitabine)

First Posted Date: 2023-07-24

Last Posted Date: 2024-11-22

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 50

Registration Number: NCT05957913

Locations: 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States

Next Generation Ingestible Sensors for Medication Adherence Measurement

Phase 3

Active, not recruiting

Conditions: Pre-Exposure Prophylaxis
HIV Infection
Antiretroviral Therapy
Adherence, Treatment
Adherence, Medication

Interventions: Device: Next-generation Reader and ID-Cap System
Drug: Biktarvy for antiretroviral therapy (ART)
Drug: Truvada for pre-exposure prophylaxis (PrEP)

First Posted Date: 2022-10-24

Last Posted Date: 2024-06-14

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 15

Registration Number: NCT05592613

Locations: 🇺🇸
Fenway Health, Boston, Massachusetts, United States

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP

Not Applicable

Completed

Conditions: Hepatitis C
Hiv
Opioid Use Disorder
Opioid Use
Risk Reduction

Interventions: Drug: Suboxone
Drug: Truvada
Drug: Mavyret

First Posted Date: 2021-11-05

Last Posted Date: 2023-04-27

Lead Sponsor: Duke University

Target Recruit Count: 17

Registration Number: NCT05108935

Locations: 🇺🇸
Duke Department of Population Health Sciences, Durham, North Carolina, United States
🇺🇸
NC Survivors Union, Greensboro, North Carolina, United States

The Role of Home Packs of HIV PEPSE in High Risk Individuals

Phase 4

Completed

Conditions: HIV-1-infection

Interventions: Drug: Maraviroc
Drug: Truvada

First Posted Date: 2021-07-16

Last Posted Date: 2021-07-22

Lead Sponsor: Guy's and St Thomas' NHS Foundation Trust

Target Recruit Count: 139

Registration Number: NCT04965662

Locations: 🇬🇧
Guy's & St. Thomas' NHS Foundation Trust, London, Greater London, United Kingdom

Pre-Exposure Prophylaxis (PrEP)- Gender Affirming Hormone Therapy (GAHT) Interactions in TGW

Phase 1

Recruiting

Conditions: Hiv
Prophylaxis
Transgender

Interventions: Drug: Truvada alone
Drug: Truvada plus Leuprolide
Drug: Truvada plus Estradiol 1 mg
Drug: Truvada plus Estradiol 6 mg
Drug: Estradiol 6 mg alone

First Posted Date: 2021-02-18

Last Posted Date: 2025-03-07

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 20

Registration Number: NCT04760691

Locations: 🇺🇸
Johns Hopkins School of Medicine Drug Development Unit, Baltimore, Maryland, United States

Safety and Drug Detection Study of Dapivirine Vaginal Ring and Oral TRUVADA® in Breastfeeding Mother-Infant Pairs

Phase 3

Completed

Conditions: HIV Infections

Interventions: Drug: Truvada Tablet
Drug: Dapivirine (DPV) Vaginal Ring (VR)-004

First Posted Date: 2019-10-25

Last Posted Date: 2023-08-04

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 394

Registration Number: NCT04140266

Locations: 🇺🇬
MU-JHU Research Collaboration (MUJHU CARE LTD) CRS, Kampala, Uganda
🇲🇼
Blantyre CRS (Johns Hopkins Research Project/College of Medicine), Blantyre, Malawi
🇿🇼
Zengeza CRS, Chitungwiza, Mashonaland East, Zimbabwe

and more 1 locations

Randomized, Open Label Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA® Use in Pregnancy

Phase 3

Completed

Conditions: HIV Infections

Interventions: Drug: Dapivirine (DPV) Vaginal Ring (VR)
Drug: Truvada Tablet

First Posted Date: 2019-05-29

Last Posted Date: 2025-01-22

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 1105

Registration Number: NCT03965923

Locations: 🇺🇬
MU-JHU Research Collaboration (MUJHU CARE LTD) CRS, Kampala, Uganda
🇿🇦
Wits RHI Shandukani Research Centre CRS, Johannesburg, Gauteng, South Africa
🇲🇼
Blantyre CRS (Johns Hopkins Research Project/College of Medicine), Blantyre, Malawi

and more 1 locations

Feasibility and Acceptability of Digital Pills to Monitor PrEP Adherence in MSM With Substance Use

Phase 4

Completed

Conditions: Substance Use Disorders
HIV/AIDS
Adherence, Medication

Interventions: Device: Digital pill
Drug: Truvada

First Posted Date: 2019-02-15

Last Posted Date: 2022-12-22

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 16

Registration Number: NCT03842436

Locations: 🇺🇸
Fenway Health, Boylston, Massachusetts, United States

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