MedPath

Emtricitabine and tenofovir disoproxil fumarate

Generic Name
Emtricitabine and tenofovir disoproxil fumarate
Indication

适用于与其他抗逆转录病毒药物联用,治疗成人和12岁(含)以上儿童的 HIV-1感染。

Pre-Exposure Prophylaxis Dosing in Pregnancy to Optimize HIV Prevention (PREP-P)

Phase 1
Withdrawn
Conditions
Pregnancy
HIV-1-infection
Interventions
First Posted Date
2019-02-08
Last Posted Date
2022-04-06
Lead Sponsor
Johns Hopkins University
Registration Number
NCT03834909

Comparative Study of PK and BE of VM-1500FDC (Fixed-dose Combination) and Elpida® With Truvada® сo-administrated 1 Daily Fasting in Healthy Subjects

Phase 1
Completed
Conditions
HIV-1-infection
Interventions
First Posted Date
2018-10-16
Last Posted Date
2018-10-30
Lead Sponsor
Viriom
Target Recruit Count
140
Registration Number
NCT03706924
Locations
🇷🇺

Private non - governmental health care institution "Scientific Clinical Center of the open joint - stock company Russian Railways", Moscow, Russian Federation

🇷🇺

Central City Clinical Hospital Reutov, Reutov, Moscow Region, Russian Federation

Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)

Phase 3
Completed
Conditions
HIV Infections
Substance Use Disorders
Interventions
Behavioral: PrEPsteps
Device: Digital pill
First Posted Date
2018-04-30
Last Posted Date
2024-06-14
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
36
Registration Number
NCT03512418
Locations
🇺🇸

Fenway Health, Boylston, Massachusetts, United States

The Prevention Options for Women Evaluation Research (POWER) Cohort

Completed
Conditions
HIV/AIDS
Interventions
First Posted Date
2018-04-06
Last Posted Date
2021-12-06
Lead Sponsor
University of Washington
Target Recruit Count
2255
Registration Number
NCT03490058
Locations
🇰🇪

Kenya Medical Research Institute, Kisumu, Kenya

🇿🇦

Desmond Tutu HIV Foundation, Cape Town, South Africa

🇿🇦

Wits Reproductive Health and HIV Institute, Johannesburg, South Africa

Immediate or Deferred Pre-exposure Prophylaxis for HIV Prevention: Safe Options for Pregnant and Lactating Women

Phase 2
Completed
Conditions
HIV-1-infection
Interventions
First Posted Date
2017-07-24
Last Posted Date
2022-11-07
Lead Sponsor
University of KwaZulu
Target Recruit Count
540
Registration Number
NCT03227731
Locations
🇿🇦

University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa

ENLIGHTEN: Establishing Novel Antiretroviral (ARV) Imaging for Hair to Elucidate Non-Adherence

Phase 4
Completed
Conditions
HIV/AIDS
Interventions
First Posted Date
2017-07-14
Last Posted Date
2019-11-22
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
36
Registration Number
NCT03218592
Locations
🇺🇸

Clinical and Translational Research Center, UNC Hospitals, Chapel Hill, North Carolina, United States

3Ps for Prevention Study (Perception, Partners, Pills)

Phase 4
Conditions
Adherence
Interventions
Behavioral: Incentivised - Conditional Cash Transfer
First Posted Date
2017-05-05
Last Posted Date
2019-02-15
Lead Sponsor
Desmond Tutu HIV Centre
Target Recruit Count
200
Registration Number
NCT03142256
Locations
🇿🇦

Desmond Tutu HIV Centre, Cape Town, South Africa

🇿🇦

Desmond Tutu HIV Foundation, Cape Town, Western Cape, South Africa

ADVANCE Study of DTG + TAF + FTC vs DTG + TDF + FTC and EFV + TDF+FTC in First-line Antiretroviral Therapy

Phase 3
Completed
Conditions
HIV-1 Infection
Interventions
First Posted Date
2017-04-20
Last Posted Date
2023-02-08
Lead Sponsor
Professor Francois Venter
Target Recruit Count
1110
Registration Number
NCT03122262
Locations
🇿🇦

Wits RHI Yeoville Clinic, Johannesburg, Gauteng, South Africa

🇿🇦

Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng, South Africa

🇿🇦

Shandukani Research Centre, Johannesburg, Gauteng, South Africa

and more 1 locations

Prevention of HIV in "Île-de-France"

Not Applicable
Recruiting
Conditions
HIV Infections
Interventions
First Posted Date
2017-04-13
Last Posted Date
2022-06-02
Lead Sponsor
ANRS, Emerging Infectious Diseases
Target Recruit Count
3257
Registration Number
NCT03113123
Locations
🇫🇷

Hôpital Européen Georges Pompidou, Paris, France

🇫🇷

Hôpital Henry Mondor, Creteil, France

🇫🇷

Hôpital Avicenne, Bobigny, France

and more 18 locations

Reversing the Epidemic in Africa With Choices in HIV Prevention (REACH)

Phase 2
Withdrawn
Conditions
HIV-1-infection
Interventions
First Posted Date
2017-03-09
Last Posted Date
2017-09-08
Lead Sponsor
International Partnership for Microbicides, Inc.
Registration Number
NCT03074786
Locations
🇿🇦

CAPRISA, eThekwini Clinical Research Site, Durban, KwaZulu-Natal, South Africa

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