MedPath

CH505 TF chTrimer

Generic Name
CH505 TF chTrimer

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Phase 1
Not yet recruiting
Conditions
HIV-1
Interventions
Other: Sodium Chloride for Injection
Biological: 3M-052-AF
First Posted Date
2024-11-08
Last Posted Date
2025-03-25
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
30
Registration Number
NCT06680479
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of California, Los Angeles CARE Center CRS, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

UCSD Antiviral Research Center CRS, San Diego, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of California, San Francisco HIV/AIDS CRS, San Francisco, California, United States

and more 22 locations

A Clinical Trial in Adult Participants Without HIV and in Overall Good Health to Evaluate the Safety and Immunogenicity of CD4BS CH505M5 Pr-NP1 Followed by CH505 TF chTrimer Boost Both Adjuvanted With Either Lipid Nanoparticles (LNPs) or 3M-052-AF + Alum

First Posted Date
2024-02-20
Last Posted Date
2025-03-26
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
42
Registration Number
NCT06267872
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Alabama CRS (Site ID: 31788), Birmingham, Alabama, United States

๐Ÿ‡บ๐Ÿ‡ธ

The Ponce de Leon Center CRS (Site ID: 5802), Atlanta, Georgia, United States

๐Ÿ‡บ๐Ÿ‡ธ

Vanderbilt Vaccine (VV) CRS (Site ID: 30352), Nashville, Tennessee, United States

and more 3 locations

Evaluating the Safety and Immunogenicity of Stabilized CH505 TF chTrimer in Healthy, HIV-uninfected Adult Participants.

Phase 1
Active, not recruiting
Conditions
HIV Infections
Interventions
First Posted Date
2021-06-07
Last Posted Date
2024-10-02
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
52
Registration Number
NCT04915768
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Vanderbilt Vaccine (VV) CRS, Nashville, Tennessee, United States

๐Ÿ‡บ๐Ÿ‡ธ

The Hope Clinic of the Emory Vaccine Center CRS, Decatur, Georgia, United States

๐Ÿ‡บ๐Ÿ‡ธ

Brigham and Women's CRS, Boston, Massachusetts, United States

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