Neostigmine
- Generic Name
- Neostigmine
- Brand Names
- Bloxiverz, Prevduo, Prostigmin
- Drug Type
- Small Molecule
- Chemical Formula
- C12H19N2O2
- CAS Number
- 59-99-4
- Unique Ingredient Identifier
- 3982TWQ96G
- Background
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
- Indication
Neostigmine is used for the symptomatic treatment of myasthenia gravis by improving muscle tone.
- Associated Conditions
- Curarization therapy, Myasthenia Gravis, Neuromuscular Blockade, Postoperative Urinary Retention (POUR), Acute Colonic Pseudo-Obstruction, Post-operative intestinal atony
- Associated Therapies
- -
Feasibility of Neostigmine for Intraoperative Neuromonitoring in Thyroid Surgery
- Conditions
- Interventions
- First Posted Date
- 2021-05-05
- Last Posted Date
- 2022-03-04
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 44
- Registration Number
- NCT04873531
- Locations
- 🇰🇷
Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea, Republic of
The Effects of Iontophoresed Vasoactive Drugs on Cutaneus Blood Flow
- Conditions
- Interventions
- First Posted Date
- 2021-03-02
- Last Posted Date
- 2021-03-02
- Lead Sponsor
- University Hospital, Linkoeping
- Target Recruit Count
- 90
- Registration Number
- NCT04777383
- Locations
- 🇸🇪
University Hospital Linköping, Linköping, Östergötland, Sweden
Reversal of Neuromuscular Blockade and Perioperative Arrhythmias
- Conditions
- Interventions
- First Posted Date
- 2021-01-22
- Last Posted Date
- 2021-01-22
- Lead Sponsor
- Başakşehir Çam & Sakura City Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT04720573
- Locations
- 🇹🇷
Istanbul Medipol University, Istanbul, Turkey
Optimizing Post-operative Recovery in Bariatric Patients With Obstructive Sleep Apnea Undergoing Outpatient Surgery: A Comparison of Sugammadex and Neostigmine
- First Posted Date
- 2020-09-30
- Last Posted Date
- 2024-04-15
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 90
- Registration Number
- NCT04570150
- Locations
- 🇺🇸
University of California San Diego, La Jolla, California, United States
Effectiveness of Sugammadex on Muscle Relaxant Reversal in Preterm Neonates
- First Posted Date
- 2020-09-28
- Last Posted Date
- 2020-09-28
- Lead Sponsor
- Alexandria University
- Target Recruit Count
- 60
- Registration Number
- NCT04566796
- Locations
- 🇪🇬
Alexandria university, Alexandria, Egypt
Neostigmine and Dexamethasone in Adductor Canal Block
- Conditions
- Interventions
- First Posted Date
- 2020-09-25
- Last Posted Date
- 2022-07-29
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 90
- Registration Number
- NCT04565301
- Locations
- 🇪🇬
Kasr Alainy hospitals, Cairo, Egypt
Sugammadex To IMprove Bowel Function
- Conditions
- Interventions
- First Posted Date
- 2020-09-14
- Last Posted Date
- 2024-07-29
- Lead Sponsor
- Oregon Health and Science University
- Target Recruit Count
- 120
- Registration Number
- NCT04546672
- Locations
- 🇺🇸
Oregon Health & Science University, Portland, Oregon, United States
Comparison of the Impacts of Sugammadex With Neostigmine on Patency of Laryngeal Opening (Glottic Aperture Angle)
- Conditions
- Interventions
- First Posted Date
- 2020-09-10
- Last Posted Date
- 2020-09-10
- Lead Sponsor
- Yonsei University
- Target Recruit Count
- 84
- Registration Number
- NCT04545099
Addition of Neostigmine to Levobupivacaine
- Conditions
- Interventions
- First Posted Date
- 2020-07-30
- Last Posted Date
- 2024-01-09
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 112
- Registration Number
- NCT04492319
- Locations
- 🇪🇬
Faculty of Medicine, Cairo University., Cairo, Egypt
IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2020-04-28
- Last Posted Date
- 2023-06-07
- Lead Sponsor
- Mansoura University
- Target Recruit Count
- 100
- Registration Number
- NCT04364607
- Locations
- 🇪🇬
Mansoura University Hospital, Mansoura, Dakahlia, Egypt
Drug Development Updates
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