Neostigmine
- Generic Name
- Neostigmine
- Brand Names
- Bloxiverz, Prevduo, Prostigmin
- Drug Type
- Small Molecule
- Chemical Formula
- C12H19N2O2
- CAS Number
- 59-99-4
- Unique Ingredient Identifier
- 3982TWQ96G
- Background
A cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier.
- Indication
Neostigmine is used for the symptomatic treatment of myasthenia gravis by improving muscle tone.
- Associated Conditions
- Curarization therapy, Myasthenia Gravis, Neuromuscular Blockade, Postoperative Urinary Retention (POUR), Acute Colonic Pseudo-Obstruction, Post-operative intestinal atony
- Associated Therapies
- -
Role of Curarization During Anesthesia for Gynecologic Surgical Laparoscopic Procedures
- First Posted Date
- 2018-05-09
- Last Posted Date
- 2018-07-10
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 100
- Registration Number
- NCT03519633
- Locations
- 🇮🇹
Campus Bio-medico, Roma, RM, Italy
Role of Curarization During Anesthesia for Gynecologic Surgical Laparotomy Procedures
- First Posted Date
- 2018-05-09
- Last Posted Date
- 2018-07-10
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 100
- Registration Number
- NCT03519724
- Locations
- 🇮🇹
Campus Bio-medico, Roma, RM, Italy
Comparison of Reversal of Neuromuscular Blockade With Sugammadex Versus Neostigmine Plus Glycopyrolate in Patients Undergoing Burn Surgery
- First Posted Date
- 2018-05-01
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- University of Kansas Medical Center
- Target Recruit Count
- 7
- Registration Number
- NCT03513406
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
Comparison Between Intraperitoneal Versus Intramuscular Neostigmine on Pattern of Postoperative GIT Motility in Patients Undergoing Laparoscopic Cholecystectomy
- First Posted Date
- 2018-04-23
- Last Posted Date
- 2018-04-23
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 160
- Registration Number
- NCT03505255
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
- Conditions
- Interventions
- First Posted Date
- 2017-10-26
- Last Posted Date
- 2021-11-16
- Lead Sponsor
- The Cleveland Clinic
- Target Recruit Count
- 69
- Registration Number
- NCT03322657
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-09-26
- Last Posted Date
- 2018-10-09
- Lead Sponsor
- Seoul National University Bundang Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT03292965
- Locations
- 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-09-08
- Last Posted Date
- 2019-05-28
- Lead Sponsor
- Virtua Health, Inc.
- Target Recruit Count
- 68
- Registration Number
- NCT03276026
- Locations
- 🇺🇸
Virtua Memorial Hospital, Mount Holly, New Jersey, United States
Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery
- First Posted Date
- 2017-08-14
- Last Posted Date
- 2019-01-15
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT03248648
- Locations
- 🇪🇬
Assiut university hospitals, Assiut, Assiut Governorate, Egypt
Intra-articular Dexmedetomidine Versus Neostigmine After Knee Arthroscopy (a Comparative Study)
- First Posted Date
- 2017-07-11
- Last Posted Date
- 2018-01-11
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT03212495
- Locations
- 🇪🇬
Assiut governorate, Assiut, Egypt
Neuromuscular Blockade on Shoulder Pain of Elderly
- Conditions
- Interventions
- First Posted Date
- 2017-07-06
- Last Posted Date
- 2020-11-25
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 100
- Registration Number
- NCT03210376
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Drug Development Updates
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