Glycopyrronium
- Generic Name
- Glycopyrronium
- Brand Names
- Bevespi, Breztri, Cuvposa, Dartisla, Enurev Breezhaler, Glycate, Glyrx, Lonhala, Prevduo, Qbrexza, Robinul, Robinul Forte, Seebri Breezhaler, Sialanar, Tovanor Breezhaler, Ultibro
- Drug Type
- Small Molecule
- Chemical Formula
- C19H28NO3
- CAS Number
- 740028-90-4
- Unique Ingredient Identifier
- A14FB57V1D
- Background
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications. Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of pept...
- Indication
Glycopyrronium formulated as a topical cloth is indicated to treat primary axillary hyperhidrosis in patients ≥9 years, and an inhalational solution is indicated for long term maintenance of airflow obstruction in COPD. A glycopyrronium intravenous and intramuscular injection is indicated in adults and pediatric patients to reduce the volume and acidity of g...
- Associated Conditions
- Airway Obstruction, Chronic Obstructive Pulmonary Disease (COPD), Increased upper airway secretion, Peptic Ulcer, Primary Axillary Hyperhidrosis, Sialorrhea, Cardiac vagal inhibitory reflexes, Cardiac vagal inhibitory reflexes caused by General Surgery, Cardiac vagal inhibitory reflexes caused by Medication, Gastric secretions, Peripheral muscarinic effects
- Associated Therapies
- -
A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2024-04-22
- Last Posted Date
- 2024-04-22
- Target Recruit Count
- 1050
- Registration Number
- NCT06376942
- Locations
- 🇮🇳
Bronchoscopy suite, PGIMER, Chandigarh, India
Effects of Glycopyrrolate on Heart Rate and Heart Rate Variability in Patients With Different Basic Heart Rate
- First Posted Date
- 2024-02-01
- Last Posted Date
- 2024-02-01
- Lead Sponsor
- Zhuan Zhang
- Target Recruit Count
- 54
- Registration Number
- NCT06237478
- Locations
- 🇨🇳
the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China
Effect of Glycopyrrolate on Nausea and Vomiting After ERCP Operation
- Conditions
- Interventions
- First Posted Date
- 2023-09-21
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- Jie Chen
- Target Recruit Count
- 130
- Registration Number
- NCT06045364
- Locations
- 🇨🇳
The Second Affiliated Hospital Of Chongqing Medical University, Chongqing, Chongqing, China
Antiperistaltic Effect and Safety of Glycopyrronium for Colonoscopic Polypectomy
- First Posted Date
- 2023-09-18
- Last Posted Date
- 2023-12-08
- Lead Sponsor
- Jie Chen
- Target Recruit Count
- 150
- Registration Number
- NCT06041984
- Locations
- 🇨🇳
The Second Affiliated Hospital Of Chongqing Medical University, Chongqing, Chongqing, China
Glycopyrrolate Prophylaxis for Prevention of Bradyarrhythmia During Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2023-08-18
- Last Posted Date
- 2023-08-28
- Lead Sponsor
- National Academy of Medical Sciences, Nepal
- Target Recruit Count
- 62
- Registration Number
- NCT05997004
- Locations
- 🇳🇵
National Academy of Medical Sciences, Kathmandu, Nepal
Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery
- First Posted Date
- 2023-06-02
- Last Posted Date
- 2023-09-29
- Lead Sponsor
- University of Missouri-Columbia
- Target Recruit Count
- 118
- Registration Number
- NCT05887375
- Locations
- 🇺🇸
University Hospital, Columbia, Missouri, United States
Effect of Perioperative Use of Glycopyrrolate on Lung Function in Patients Under General Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2023-01-20
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Zhuan Zhang
- Target Recruit Count
- 90
- Registration Number
- NCT05693246
- Locations
- 🇨🇳
the Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu, China
Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and Ondansetron
- Conditions
- Interventions
- First Posted Date
- 2022-03-03
- Last Posted Date
- 2023-02-24
- Target Recruit Count
- 480
- Registration Number
- NCT05265507
- Locations
- 🇨🇳
The Second Affiliated Hospital, Chongqing Medical University, Chongqing, Chongqing, China
Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture
- Conditions
- Interventions
- First Posted Date
- 2021-11-11
- Last Posted Date
- 2024-04-19
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 18
- Registration Number
- NCT05116930
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD
- Conditions
- Interventions
- First Posted Date
- 2020-03-25
- Last Posted Date
- 2024-10-09
- Lead Sponsor
- Chiesi Farmaceutici S.p.A.
- Target Recruit Count
- 2934
- Registration Number
- NCT04320342
- Locations
- 🇺🇸
Chiesi Clinical Trial Site 840421, Kingwood, West Virginia, United States
🇺🇸Chiesi Clinical Trial Site 840201, Morgantown, West Virginia, United States
🇨🇦Chiesi Clinical Trial Site 124103, Edmonton, Alberta, Canada
Drug Development Updates
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