Glycopyrronium

Generic Name
Glycopyrronium
Brand Names
Bevespi, Breztri, Cuvposa, Dartisla, Enurev Breezhaler, Glycate, Glyrx, Lonhala, Prevduo, Qbrexza, Robinul, Robinul Forte, Seebri Breezhaler, Sialanar, Tovanor Breezhaler, Ultibro
Drug Type
Small Molecule
Chemical Formula
C19H28NO3
CAS Number
740028-90-4
Unique Ingredient Identifier
A14FB57V1D
Background

Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications. Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of pept...

Indication

Glycopyrronium formulated as a topical cloth is indicated to treat primary axillary hyperhidrosis in patients ≥9 years, and an inhalational solution is indicated for long term maintenance of airflow obstruction in COPD. A glycopyrronium intravenous and intramuscular injection is indicated in adults and pediatric patients to reduce the volume and acidity of g...

Associated Conditions
Airway Obstruction, Chronic Obstructive Pulmonary Disease (COPD), Increased upper airway secretion, Peptic Ulcer, Primary Axillary Hyperhidrosis, Sialorrhea, Cardiac vagal inhibitory reflexes, Cardiac vagal inhibitory reflexes caused by General Surgery, Cardiac vagal inhibitory reflexes caused by Medication, Gastric secretions, Peripheral muscarinic effects
Associated Therapies
-
Clinical Trials
Related News

Investigation of Sugammadex in Outpatient Urological Procedures

First Posted Date
2017-05-03
Last Posted Date
2020-09-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
54
Registration Number
NCT03138967
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy

First Posted Date
2017-04-12
Last Posted Date
2019-04-29
Lead Sponsor
West Virginia University
Target Recruit Count
84
Registration Number
NCT03111121
Locations
🇺🇸

WVU Healthcare Ruby Memorial Hospital, Morgantown, West Virginia, United States

Benefits of Glycopyrrolate on Intubation With Rigid-videostylet (OptiScope®)

Not Applicable
Completed
Conditions
Cholecystitis, Acute
Interventions
Drug: Glycopyrrolate
First Posted Date
2017-02-10
Last Posted Date
2018-05-24
Lead Sponsor
Eunah Cho, MD
Target Recruit Count
78
Registration Number
NCT03050242
Locations
🇰🇷

Kangbuk Samsung Hospital, Seoul, Korea, Republic of

Effect of a LAMA and a uLABA on the Methacholine Dose-response Curve

Phase 4
Completed
Conditions
Asthma
Interventions
Drug: Glycopyrronium
Drug: Indacaterol
First Posted Date
2016-11-02
Last Posted Date
2017-06-14
Lead Sponsor
University of Saskatchewan
Target Recruit Count
31
Registration Number
NCT02953041
Locations
🇨🇦

Asthma Research Lab, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Minimizing Nausea and Vomiting During Spinals for CS

Phase 4
Terminated
Conditions
Nausea
Vomiting
Interventions
Drug: Normal Saline
Drug: Glycopyrrolate
First Posted Date
2016-08-19
Last Posted Date
2020-06-09
Lead Sponsor
Kokila N Thenuwara
Target Recruit Count
22
Registration Number
NCT02872935
Locations
🇺🇸

University of Iowa, Iowa City, Iowa, United States

Effects of Long Acting Bronchodilators on CARDiac Autonomic Control in Chronic Obstructive Pulmonary Disease (COPD)

First Posted Date
2016-08-18
Last Posted Date
2021-08-03
Lead Sponsor
Centre Hospitalier Universitaire de Besancon
Target Recruit Count
42
Registration Number
NCT02872090
Locations
🇫🇷

Centre Hospitalier Régional Universitaire, Besançon, France

Study to Determine if Administration of Sugammadex Impacts Hospital Efficiency

First Posted Date
2016-08-09
Last Posted Date
2019-04-12
Lead Sponsor
University of South Florida
Target Recruit Count
50
Registration Number
NCT02860507

Decision Support for Intraoperative Low Blood Pressure

Not Applicable
Completed
Conditions
Hypotension
Interventions
Procedure: Attending real-time decision support
Procedure: In-room real-time decision support
Procedure: Attending feedback emails
Procedure: In-room provider feedback emails
Device: Anesthesia Information Management System (AIMS)
Device: Perioperative Data Warehouse (PDW)
Procedure: General anesthesia
Device: Pager system
Procedure: Central neuraxial anesthesia
Procedure: Non-cardiac surgery
Drug: Propofol
Drug: Sevoflurane
Drug: Desflurane
Drug: Isoflurane
Drug: Ephedrine
Drug: Phenylephrine
Drug: Norepinephrine
Drug: Epinephrine
Drug: Dobutamine
Drug: Dopamine
Drug: Isoproterenol
Drug: Milrinone
Drug: Atropine
Drug: Glycopyrrolate
Drug: Vasopressin
Drug: Terlipressin
Drug: Sodium Chloride 0.9%
Drug: Ringer's lactate
Drug: Hydroxyethyl starch solutions
Drug: Fresh Frozen Plasma
Drug: Packed Red Blood Cells
Drug: Albumin solutions
Drug: Plasma-Lyte
Drug: Lidocaine
Drug: Bupivacaine
Drug: Levobupivacaine
Drug: Ropivacaine
Drug: Mepivacaine
Drug: Tetracaine
Drug: Prilocaine
Drug: Procaine
Drug: Chloroprocaine
Drug: Benzocaine
Drug: Articaine
First Posted Date
2016-04-04
Last Posted Date
2019-05-16
Lead Sponsor
Vanderbilt University Medical Center
Target Recruit Count
22435
Registration Number
NCT02726620
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Duration of Long Acting Muscarinic Antagonist (LAMA) Bronchoprotection Against Methacholine Challenge

First Posted Date
2015-12-04
Last Posted Date
2016-04-20
Lead Sponsor
University of Saskatchewan
Target Recruit Count
13
Registration Number
NCT02622243
Locations
🇨🇦

Asthma Research Lab, Saskatoon, Saskatchewan, Canada

Clozapine-induced Hypersalivation - Feasibility Trial

Phase 1
Completed
Conditions
Sialorrhea
Interventions
Drug: Hyoscine
Other: Placebo
Drug: Glycopyrrolate
First Posted Date
2015-11-24
Last Posted Date
2018-02-28
Lead Sponsor
Mersey Care NHS Trust
Target Recruit Count
29
Registration Number
NCT02613494
Locations
🇬🇧

Lancashire Care NHS Foundation Trust, Preston, Lancashire, United Kingdom

🇬🇧

Mersey Care NHS Trust, Liverpool, Merseyside, United Kingdom

© Copyright 2024. All Rights Reserved by MedPath
HomeTerms & ConditionsPrivacy Policy