Glycopyrronium
- Generic Name
- Glycopyrronium
- Brand Names
- Bevespi, Breztri, Cuvposa, Dartisla, Enurev Breezhaler, Glycate, Glyrx, Lonhala, Prevduo, Qbrexza, Robinul, Robinul Forte, Seebri Breezhaler, Sialanar, Tovanor Breezhaler, Ultibro
- Drug Type
- Small Molecule
- Chemical Formula
- C19H28NO3
- CAS Number
- 740028-90-4
- Unique Ingredient Identifier
- A14FB57V1D
- Background
Glycopyrronium, also known as NVA237 or glycopyrrolate, is a racemic mixture of two enantiomers. They are both quaternary ammonium compounds and long acting muscarinic antagonists. It is one of the most commonly prescribed anticholinergic medications. Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of pept...
- Indication
Glycopyrronium formulated as a topical cloth is indicated to treat primary axillary hyperhidrosis in patients ≥9 years, and an inhalational solution is indicated for long term maintenance of airflow obstruction in COPD. A glycopyrronium intravenous and intramuscular injection is indicated in adults and pediatric patients to reduce the volume and acidity of g...
- Associated Conditions
- Airway Obstruction, Chronic Obstructive Pulmonary Disease (COPD), Increased upper airway secretion, Peptic Ulcer, Primary Axillary Hyperhidrosis, Sialorrhea, Cardiac vagal inhibitory reflexes, Cardiac vagal inhibitory reflexes caused by General Surgery, Cardiac vagal inhibitory reflexes caused by Medication, Gastric secretions, Peripheral muscarinic effects
- Associated Therapies
- -
Use of High Resolution Colonic Manometry in Studying Motility
- Conditions
- Interventions
- First Posted Date
- 2015-10-14
- Last Posted Date
- 2021-09-28
- Lead Sponsor
- James J. Peters Veterans Affairs Medical Center
- Registration Number
- NCT02574611
- Locations
- 🇺🇸
James J. Peters VA Medical Center, Bronx, New York, United States
Chronotropic Incompetence in Patients With HFpEF
- Conditions
- Interventions
- First Posted Date
- 2015-08-14
- Last Posted Date
- 2020-08-06
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT02524145
- Locations
- 🇺🇸
The Institute for Exercise and Environmental Medicine, Dallas, Texas, United States
Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine
- First Posted Date
- 2015-04-30
- Last Posted Date
- 2015-05-01
- Lead Sponsor
- Inje University
- Target Recruit Count
- 84
- Registration Number
- NCT02430272
- Locations
- 🇰🇷
Ilsan Paik hospital, Goyang-si, Gyeonggi-do, Korea, Republic of
Anesthetics in Rhytidoplasty - A Comparison Study
- First Posted Date
- 2015-04-07
- Last Posted Date
- 2015-04-07
- Lead Sponsor
- Mercy Facial Plastic Surgery Center
- Target Recruit Count
- 30
- Registration Number
- NCT02410460
- Locations
- 🇺🇸
Mercy Facial Plastic Surgery Center, Springfield, Missouri, United States
Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2018-04-17
- Lead Sponsor
- Ottawa Hospital Research Institute
- Target Recruit Count
- 28
- Registration Number
- NCT02382198
- Locations
- 🇨🇦
The Ottawa Hospital - Civic Campus, Ottawa, Ontario, Canada
🇨🇦Toronto Western Hospital, Toronto, Ontario, Canada
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
- Conditions
- Interventions
- First Posted Date
- 2015-03-02
- Last Posted Date
- 2018-06-27
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 56
- Registration Number
- NCT02375217
- Locations
- 🇱🇧
AUBMC, Beirut, Lebanon
Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy
- First Posted Date
- 2014-12-31
- Last Posted Date
- 2018-11-30
- Lead Sponsor
- B.P. Koirala Institute of Health Sciences
- Target Recruit Count
- 90
- Registration Number
- NCT02327923
- Locations
- 🇳🇵
BP Koirala Institute of Health Sciences, Dharan, Sunsari District, Nepal
A 12-week Study to Evaluate the Efficacy and Safety of Umeclidinium 62.5 Microgram (mcg) Compared With Glycopyrronium 44 mcg in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
- Conditions
- Interventions
- First Posted Date
- 2014-09-10
- Last Posted Date
- 2018-05-02
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 1036
- Registration Number
- NCT02236611
- Locations
- 🇸🇪
GSK Investigational Site, Stockholm, Sweden
Effect of Glycopyrrolate and Atropine on Catheter-Related Bladder Discomfort
- Conditions
- Interventions
- First Posted Date
- 2014-08-29
- Last Posted Date
- 2014-10-28
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 76
- Registration Number
- NCT02228473
- Locations
- 🇰🇷
Seoul National University of Hospital, Seoul, Korea, Republic of, Korea, Republic of
Acute Effect of Aclidinium on Hyperinflation and Ventilation Inhomogeneity in Severe COPD Patients
- Conditions
- Interventions
- First Posted Date
- 2014-07-03
- Last Posted Date
- 2014-10-29
- Lead Sponsor
- University of Milan
- Target Recruit Count
- 37
- Registration Number
- NCT02181023
- Locations
- 🇮🇹
Fondazione Salvatore Maugeri, Milan, Italy
Drug Development Updates
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