Methylprednisolone

Generic Name
Methylprednisolone
Brand Names
Depo-medrol, Depo-medrol With Lidocaine, Hybrisil, Medrol, Medroloan Suik, Readysharp-p40, Readysharp-p80
Drug Type
Small Molecule
Chemical Formula
C22H30O5
CAS Number
83-43-2
Unique Ingredient Identifier
X4W7ZR7023
Background

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.
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Indication

Oral and intramuscular methylprednisolone are indicated for a number of endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, nervous system, and other disorders. Intra-articular and soft tissue injections are indicated for short term treatment of acute gouty arthritis, acute an...

Associated Conditions
Acute Gouty Arthritis, Acute Leukemia, Allergic Conjunctivitis (AC), Allergic corneal marginal ulcers, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Aponeurosis contusion, Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hemolytic Anemia, Berylliosis, Bronchial Asthma, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Degenerative Joint Disease, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Gout, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Inflammatory Reaction of the Cysts, Iridocyclitis, Iritis, Keloids Scars, Keratitis, Leukemias, Lichen Planus (LP), Lichen simplex chronicus, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Nummular Dermatitis, Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pemphigus, Perennial Allergic Rhinitis (PAR), Polymyositis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Seasonal Allergic Rhinitis, Seborrheic Dermatitis, Eczematous, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Tendonitis exacerbated, Transfusion Reactions, Trichinosis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Multiple sclerosis exacerbation, Acute nonspecific tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Articular inflammation, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Idiopathic eosinophilic pneumonias, Inflammatory dermatoses of the scalp, Localized Hypertrophic, Inflammatory, Infiltrated granuloma annulare lesions, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
Associated Therapies
Palliative Treatment

Medrol Dose Packs for Post-Operative Pain Control

Early Phase 1
Conditions
Interventions
First Posted Date
2024-06-11
Last Posted Date
2024-06-11
Lead Sponsor
University of Utah
Target Recruit Count
90
Registration Number
NCT06453083
Locations
🇺🇸

University of Utah Orthopaedic Center, Salt Lake City, Utah, United States

Depo-Medrol on Psoas After LLIF

First Posted Date
2023-07-03
Last Posted Date
2023-07-03
Lead Sponsor
Hardeep Singh
Target Recruit Count
80
Registration Number
NCT05929755
Locations
🇺🇸

UConn Health, Farmington, Connecticut, United States

The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-05-09
Last Posted Date
2023-12-04
Lead Sponsor
Leiden University Medical Center
Target Recruit Count
148
Registration Number
NCT05851508
Locations
🇳🇱

Leiden University Medical Centre, Leiden, Zuid Holland, Netherlands

Plantar Fasciitis, Operation or Conservative Treatment

First Posted Date
2015-05-19
Last Posted Date
2018-07-11
Lead Sponsor
Bispebjerg Hospital
Target Recruit Count
30
Registration Number
NCT02448316
Locations
🇩🇰

Institute of Sports Medicine Copenhagen, Bispebjerg Hospital, Kobenhavn, Denmark

Caustic Esophageal Burns in Children and High Doses of Methylprednisolone

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-12-05
Last Posted Date
2013-12-05
Lead Sponsor
Sisli Hamidiye Etfal Training and Research Hospital
Target Recruit Count
83
Registration Number
NCT02002078

Anabolic and Inflammatory Responses to Short-Term Testosterone Administration in Older Men

First Posted Date
2009-08-12
Last Posted Date
2018-05-08
Lead Sponsor
The University of Texas Medical Branch, Galveston
Target Recruit Count
29
Registration Number
NCT00957801
Locations
🇺🇸

The University of Texas Medical Branch at Galveston, Galveston, Texas, United States

Epidural Study of Patients With Chronic Lower Back Pain

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2009-04-23
Last Posted Date
2012-02-08
Lead Sponsor
Hamilton Health Sciences Corporation
Target Recruit Count
252
Registration Number
NCT00887003
Locations
🇨🇦

Hamilton General Hospital, Hamilton, Ontario, Canada

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