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Phenylalanine

Generic Name
Phenylalanine
Brand Names
Aminosyn II 7 %, Sulfite-free, Aminosyn-PF 7%, Clinimix 2.75/5, Clinimix E 2.75/5, Clinisol 15, Freamine 6.9, Freamine III 10, Hepatamine 8, Nephramine, Olimel, Periolimel, Plenamine, Premasol, Primene, Procalamine 3, Prosol, Travasol 10, Trophamine 10 %
Drug Type
Small Molecule
Chemical Formula
C9H11NO2
CAS Number
63-91-2
Unique Ingredient Identifier
47E5O17Y3R
Background

Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, dopamine, noradrenalin (norepinephrine), and thyroxine.

Indication

L-phenylalanine may be helpful in some with depression. It may also be useful in the treatment of vitiligo. There is some evidence that L-phenylalanine may exacerbate tardive dyskinesia in some schizophrenic patients and in some who have used neuroleptic drugs.

Associated Therapies
Amino acid supplementation

F 18 T807 PET (Positron Emission Tomograph )Scan for HIV Infected & Uninfected

Completed
Conditions
Alzheimer Disease
HIV
Interventions
First Posted Date
2017-09-12
Last Posted Date
2020-09-22
Lead Sponsor
Tammie L. S. Benzinger, MD, PhD
Target Recruit Count
60
Registration Number
NCT03279523
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy

Phase 4
Conditions
Anemia During Pregnancy
Interventions
Dietary Supplement: L (lactoferrin)
First Posted Date
2017-06-28
Last Posted Date
2018-07-09
Lead Sponsor
Abdelwahed, Mai Mahmoud Mohamed, M.D.
Target Recruit Count
130
Registration Number
NCT03202615
Locations
🇪🇬

Mai Mahmoud Mohamed, Alexandria, Egypt

Study to Assess the Taste Profile of Different ALS-008176 Oral Liquid Formulations in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Formulation A (ALS-008176)
Drug: Formulation G1 (ALS-008176)
Drug: Formulation B (ALS-008176)
Drug: Formulation G2 (ALS-008176)
Drug: Formulation C (ALS-008176)
Drug: Formulation G3 (ALS-008176)
Drug: Formulation H1 (ALS-008176)
Drug: Formulation E (ALS-008176)
Drug: Formulation H2 (ALS-008176)
Drug: Formulation H3 (ALS-008176)
First Posted Date
2016-06-27
Last Posted Date
2025-02-03
Lead Sponsor
Janssen Research & Development, LLC
Target Recruit Count
11
Registration Number
NCT02813460

Efficacy of Three Toothpastes Using an in Situ Caries Model

Not Applicable
Completed
Conditions
Dental Caries
Interventions
Drug: 0.3%ZnCl2, 0.5% sodium citrate, 1150ppm F
Other: 0 ppm F
Drug: 0.425 % w/w phytate,1150ppm F
Drug: 0.85 % w/w phytate,1150ppm F
Drug: 0.85 % w/w phytate,0.3%ZnCl2 0.5% sodium citrate, 1150ppm F
First Posted Date
2016-04-26
Last Posted Date
2017-10-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
58
Registration Number
NCT02751320
Locations
🇺🇸

GSK Investigational Site, Indianapolis, Indiana, United States

F 18 T807 Tau PET Imaging of Frontotemporal Dementia (FTD)

Phase 2
Withdrawn
Conditions
Alzheimer Disease
Interventions
First Posted Date
2016-03-14
Last Posted Date
2024-03-13
Lead Sponsor
Tammie L. S. Benzinger, MD, PhD
Registration Number
NCT02707978
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Study to Evaluate Taste Profile of Different JNJ-53718678 Oral Liquid Formulations in Healthy Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Formulation A
Drug: Formulation M1
Drug: Formulation B
Drug: Formulation M2
Drug: Formulation C
Drug: Formulation M3
Drug: Formulation N1
Drug: Formulation E
Drug: Formulation N2
Drug: Formulation N3
First Posted Date
2015-04-27
Last Posted Date
2018-05-15
Lead Sponsor
Janssen Sciences Ireland UC
Target Recruit Count
12
Registration Number
NCT02426632

F 18 T807 Tau PET Imaging of Alzheimer's Disease

Recruiting
Conditions
Alzheimer Disease
Interventions
First Posted Date
2015-04-10
Last Posted Date
2024-07-17
Lead Sponsor
Tammie L. S. Benzinger, MD, PhD
Target Recruit Count
900
Registration Number
NCT02414347
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

F 18 T807 Tau PET Imaging of Progressive Posterior Cortical Dysfunction (IND 123119, Protocol E)

Completed
Conditions
Progressive Posterior Cortical Dysfunction (PPCD)
Alzheimer Disease
Interventions
First Posted Date
2015-04-10
Last Posted Date
2021-01-19
Lead Sponsor
Tammie L. S. Benzinger, MD, PhD
Target Recruit Count
20
Registration Number
NCT02414282
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)

Conditions
Alzheimer Disease
Interventions
First Posted Date
2015-04-10
Last Posted Date
2024-07-17
Lead Sponsor
Washington University School of Medicine
Target Recruit Count
130
Registration Number
NCT02414178
Locations
🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

A Crossover Study to Evaluate Relative Bioavailability of Simeprevir Age-appropriate Oral Formulation Candidates Compared With 150-milligram (mg) Oral Capsule in Healthy Adult Participants

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: Treatment A
Drug: Treatment B
Drug: Treatment E
Drug: Treatment C
First Posted Date
2015-03-11
Last Posted Date
2017-09-07
Lead Sponsor
Janssen Sciences Ireland UC
Target Recruit Count
48
Registration Number
NCT02385071
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