Sodium fluoride

Generic Name
Sodium fluoride
Brand Names
60 Second Taste, Clinpro 5000, Ctx4 Gel, Denta 5000 Plus, Denticare Denti Foam, Denticare Neutral, Denticare Pro Gel, Fluorishield, Fluoritab, Flura-drops, Gelato Sodium Fluoride, Kolorz, Ludent, Meijer, Mvc-fluoride, Neutracare, Neutramaxx, Oral-B Minute-foam, Oral-B Neutra, Pcxx Neutral Foam, Pcxx Neutral Rinse, Perfect Choice One Minute, Prevident, Prevident 5000 Sensitive, Prevident Dental Rinse, Prodenrx Rinse, Zooby Fluoride Foam
Drug Type
Small Molecule
Chemical Formula
FNa
CAS Number
7681-49-4
Unique Ingredient Identifier
8ZYQ1474W7
Background

Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as Fluoride ion F-18. Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated drinking water showed less tooth decay than those without fluoridated water. The use of fluoride in dental practice began in the 1940s. Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care. According to the American Dental Association (ADA), thorough evidence reviews have indicated that the use of fluoride to prevent and control dental caries is safe when used correctly and is highly effective in reducing the prevalence of caries.

Indication

Sodium fluoride in the oral or topical form is indicated for the prevention and control of dental caries and for the maintenance of dental health. Fluoride supplements in the form of tablets and other formulas may be prescribed to prevent tooth decay in high-risk children aged 6 months to 16 years old whose drinking water source contains low fluoride concentrations.

Associated Conditions
Cavity, Dental Cavity, Dental Decay, Dental Health, Enamel Caries, Partial Denture Wearers Wear of the Natural Enamel, Sensitivity, Tooth, Trace Element Deficiency, Wear of the Natural Enamel caused by teeth grinding
Associated Therapies
Parenteral Nutrition

Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental Erosion

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2012-08-06
Last Posted Date
2015-01-26
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
56
Registration Number
NCT01657903
Locations
🇺🇸

Indiana University School of Dentistry, Indianapolis, Indiana, United States

Effect of Fluoride in a Dentifrice on Remineralization of Erosive Lesions

First Posted Date
2012-07-16
Last Posted Date
2014-07-24
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
72
Registration Number
NCT01641237
Locations
🇺🇸

Indiana University School of Dentistry, Indianapolis, Indiana, United States

Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental Erosion

First Posted Date
2010-05-24
Last Posted Date
2015-01-01
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
36
Registration Number
NCT01128972
Locations
🇺🇸

Indiana University School of Dentistry, Indianapolis, Indiana, United States

Therapeutic Effect of Two Fluoride Varnishes on White Spot Lesions: a Clinical Study

First Posted Date
2008-07-28
Last Posted Date
2008-07-28
Lead Sponsor
University of Pernambuco
Target Recruit Count
45
Registration Number
NCT00723515
Locations
🇧🇷

University of Pernambuco, Camaragibe, Pernambuco, Brazil

The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries

First Posted Date
2008-02-11
Last Posted Date
2008-02-11
Lead Sponsor
Universidade Federal do Ceara
Target Recruit Count
69
Registration Number
NCT00612469
Locations
🇧🇷

School of Dentistry, Department of Clinical Dentistry, Federal University of Ceara, Fortaleza, Ceara, Brazil

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