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Tranylcypromine

Generic Name
Tranylcypromine
Brand Names
Parnate
Drug Type
Small Molecule
Chemical Formula
C9H11N
CAS Number
155-09-9
Unique Ingredient Identifier
3E3V44J4Z9

Overview

A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).

Background

A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).

Indication

用于抑郁症。

Associated Conditions

  • Depressive Episodes

FDA Approved Products

Tranylcypromine
Manufacturer:Solco Healthcare US, LLC
Route:ORAL
Strength:10 mg in 1 1
Approved: 2022/07/07
NDC:43547-655
TRANYLCYPROMINE SULFATE
Manufacturer:Strides Pharma Science Limited
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/05/26
NDC:64380-176
Tranylcypromine
Manufacturer:Marlex Pharmaceuticals, Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2023/03/03
NDC:10135-739
TRANYLCYPROMINE SULFATE
Manufacturer:Par Pharmaceutical, Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2019/11/19
NDC:49884-032
PARNATE
Manufacturer:Concordia Pharmaceuticals Inc.
Route:ORAL
Strength:10 mg in 1 1
Approved: 2021/03/01
NDC:59212-447

Singapore Approved Products

No Singapore products found for this drug

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