Hyaluronic acid
- Generic Name
- Hyaluronic acid
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C28H44N2O23
- CAS Number
- 9004-61-9
- Unique Ingredient Identifier
- S270N0TRQY
- Background
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not limited to woun...
- Indication
The intra-articular preparations of hyaluronic acid are indicated for knee pain associated with osteoarthritis. Hyaluronic acid is used in cosmetic applications to prevent and reduce the appearance of wrinkles on the face, and as a dermal filler to correct facial imperfections or other imperfections on other parts of the body. It is frequently an ingredient ...
- Associated Conditions
- Actinic Keratosis (AK), Burns, Chronic Skin Ulcers, Conjunctivitis, Dehydration, Dermabrasion, Dermatosis, Dry Eyes, Facial Defect, Interstitial Cystitis, Keratoconjunctivitis, Ocular Irritation, Osteoarthritis (OA), Pain of the knee, Seasonal Allergic Conjunctivitis, Skin Burn, Skin Irritation, Skin fissures, Tissue Adhesions, Varicose Ulcers, Wound, Eye discomfort, Facial fine wrinkling, Sensation of burning in the eyes, Superficial Wounds
- Associated Therapies
- Dermal Filler, Promotion of wound healing, Synovial Fluid Lubrication
Controlling Post-extraction Complications of Impacted Mandibular Third Molar
- Conditions
- Interventions
- First Posted Date
- 2021-03-25
- Last Posted Date
- 2021-07-22
- Lead Sponsor
- Al-Azhar University
- Target Recruit Count
- 72
- Registration Number
- NCT04816253
- Locations
- 🇸🇦
Vision college, Jeddah, Saudi Arabia
Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing Loss
- Conditions
- Interventions
- First Posted Date
- 2021-02-23
- Last Posted Date
- 2024-10-24
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 15
- Registration Number
- NCT04766853
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Hyaluronic Acid for Residual Periodontal Pockets Adjunctive Treatment
- First Posted Date
- 2021-01-08
- Last Posted Date
- 2021-01-08
- Lead Sponsor
- University of Roma La Sapienza
- Target Recruit Count
- 144
- Registration Number
- NCT04702334
Wireless Micropump in Dry Eye Patients
- First Posted Date
- 2020-12-16
- Last Posted Date
- 2020-12-16
- Lead Sponsor
- Tianjin Eye Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT04667819
- Locations
- 🇨🇳
Tianjin Eye Hospital, Tianjin, China
Prolotherapy Intervention Effect in Patient With Knee Osteoarthritis
- Conditions
- Interventions
- First Posted Date
- 2020-09-22
- Last Posted Date
- 2020-11-19
- Lead Sponsor
- Hasanuddin University
- Target Recruit Count
- 36
- Registration Number
- NCT04557943
- Locations
- 🇮🇩
Hasanuddin University, Faculty of Medicine, Makassar, South Sulawesi, Indonesia
Phonosurgical Augmentation After Laser Resection of Early Glottic Carcinoma
- First Posted Date
- 2020-08-25
- Last Posted Date
- 2020-08-25
- Lead Sponsor
- Ayhman Al Afif
- Target Recruit Count
- 39
- Registration Number
- NCT04525066
Intra-articular Oxygen-ozone Therapy for the Treatment of Knee Osteoarthritis Compared With Hyaluronic Acid
- First Posted Date
- 2020-06-11
- Last Posted Date
- 2020-06-16
- Lead Sponsor
- Humanitas Clinical and Research Center
- Target Recruit Count
- 120
- Registration Number
- NCT04426721
- Locations
- 🇮🇹
Humanitas Clinical and Research Hospital, Rozzano, Milano, Italy
Injection Therapy in Patients With Lateral Epicondylitis
- Conditions
- Interventions
- First Posted Date
- 2020-05-20
- Last Posted Date
- 2020-05-20
- Lead Sponsor
- Hacettepe University
- Target Recruit Count
- 32
- Registration Number
- NCT04395417
- Locations
- 🇹🇷
Hakan Apaydın, Ankara, Turkey
Use of Tranexamic Acid in Facial Fillers
- Conditions
- Interventions
- First Posted Date
- 2020-05-04
- Last Posted Date
- 2022-07-26
- Lead Sponsor
- University of Wisconsin, Madison
- Registration Number
- NCT04373603
- Locations
- 🇺🇸
University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States
To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid
- Conditions
- Interventions
- First Posted Date
- 2019-12-13
- Last Posted Date
- 2019-12-13
- Lead Sponsor
- Dr. Himanshu Bansal Foundation
- Target Recruit Count
- 100
- Registration Number
- NCT04198467
Drug Development Updates
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