Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections. It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus. Ketoconazole was first approved in an oral formulation for systemic use by...
Ketoconazole is used in the treatment or prevention of fungal infections including blastomycosis, candidiasis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis. In Europe, it is also used in the treatment of endogenous Cushing's syndrome.
GSK Investigational Site, Buffalo, New York, United States
University of California, San Francisco, San Francisco, California, United States
City of Hope, Duarte, California, United States
Karmanos Cancer Institute / Wayne State University, Detroit, Michigan, United States
St. Francis Medical Group Oncology & Hematology Specialists, Indianapolis, Indiana, United States
Site Reference ID/Investigator# 25068, San Antonio, Texas, United States
PRACS Institute, Ltd. - Cetero Research, Fargo, North Dakota, United States
GSK Investigational Site, Madison, Wisconsin, United States
GSK Investigational Site, Seoul, Korea, Republic of
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Pfizer Investigational Site, Rueil Malmaison, France
University of California, Davis Cancer Center, Sacramento, California, United States
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