Cyproterone acetate

Generic Name
Cyproterone acetate
Brand Names
Androcur, Cléo -35, Cyestra-35, Diane
Drug Type
Small Molecule
Chemical Formula
C24H29ClO4
CAS Number
427-51-0
Unique Ingredient Identifier
4KM2BN5JHF
Background

An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.

Indication

For the palliative treatment of patients with advanced prostatic carcinoma.

Associated Conditions
Menstrual Irregularities, Osteoporosis, Paraphilia, Postmenopausal Osteoporosis, Primary Amenorrhoea, Secondary Amenorrhea, Severe Acne, Advanced carcinoma of the prostate, Metastatic Carcinoma of the Prostate
Associated Therapies
Hormone Replacement Therapy

The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate

First Posted Date
2021-04-19
Last Posted Date
2021-07-21
Lead Sponsor
Benha University
Target Recruit Count
60
Registration Number
NCT04848181
Locations
🇪🇬

Benha University, Banhā, Qalyubia, Egypt

Effects of Sex Steroids on the Serotonin System

First Posted Date
2016-03-22
Last Posted Date
2018-10-15
Lead Sponsor
Medical University of Vienna
Target Recruit Count
92
Registration Number
NCT02715232
Locations
🇦🇹

Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

Phlebotomy and Polycystic Ovary Syndrome

First Posted Date
2015-06-02
Last Posted Date
2022-07-27
Lead Sponsor
Manuel Luque Ramírez
Target Recruit Count
37
Registration Number
NCT02460445
Locations
🇪🇸

Diabetes, Obesity and Human Reproduction Research Group, Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain

Sex Steroids and the Serotonin Transporter

First Posted Date
2010-02-09
Last Posted Date
2014-01-03
Lead Sponsor
Medical University of Vienna
Target Recruit Count
32
Registration Number
NCT01065220
Locations
🇦🇹

Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria

Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma

First Posted Date
2009-11-11
Last Posted Date
2015-07-30
Lead Sponsor
Takeda
Target Recruit Count
311
Registration Number
NCT01011751
Locations
🇫🇷

Professor Jacques IRANI, Poitiers, France

Comparison of Two Pharmacological Treatments of Pedophilia

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2008-01-28
Last Posted Date
2009-07-13
Lead Sponsor
Institut National de la Santé Et de la Recherche Médicale, France
Target Recruit Count
48
Registration Number
NCT00601276
Locations
🇫🇷

Federation d'Endocrinologie, Hopital NeuroCardiologique, Bron, France

🇫🇷

Centre MédicoPsychologique CMPG21, EPS Perray Vaucluse, Paris, France

🇫🇷

Service de Psychiatrie, Hopital Foch, Suresnes, France

and more 1 locations

Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

Phase 3
Conditions
First Posted Date
2006-08-15
Last Posted Date
2013-08-26
Lead Sponsor
St. Bartholomew's Hospital
Target Recruit Count
900
Registration Number
NCT00363285
Locations
🇬🇧

Scarborough General Hospital, Scarborough, England, United Kingdom

🇬🇧

Saint Bartholomew's Hospital, London, England, United Kingdom

Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2013-03-26
Lead Sponsor
Barr Laboratories
Registration Number
NCT00005623
Locations
🇺🇸

Barr Laboratories, Incorporated, Pomona, New York, United States

Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2021-06-23
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
1386
Registration Number
NCT00003653
Locations
🇨🇦

BCCA - Cancer Centre for the Southern Interior, Kelowna, British Columbia, Canada

🇨🇦

BCCA - Fraser Valley Cancer Centre, Surrey, British Columbia, Canada

🇨🇦

Clinical Research Unit at Vancouver Coastal, Vancouver, British Columbia, Canada

and more 26 locations
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