Morphine
- Generic Name
- Morphine
- Brand Names
- Arymo, Avinza, Doloral, Duramorph, Embeda, Infumorph, Kadian, M-ediat, M-eslon, MSIR, Mitigo, Ms Contin, Statex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 57-27-2
- Unique Ingredient Identifier
- 76I7G6D29C
- Background
Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as codeine, fentanyl, methadone, hydrocodone, hydromorp...
- Indication
Morphine is used for the management of chronic, moderate to severe pain.
Opiods, including morphine, are effective for the short term management of pain. Patients taking opioids long term may need to be monitored for the development of physical dependence, addiction disorder, and drug abuse.
- Associated Conditions
- Chronic Pain, Severe Pain
- Associated Therapies
- -
Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain
- Conditions
- Interventions
- First Posted Date
- 2023-12-07
- Last Posted Date
- 2024-06-24
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 495
- Registration Number
- NCT06160778
- Locations
- 🇨🇦
Alberta Children's Hospital Emergency Department, Calgary, Alberta, Canada
Intrathecal Morphine vs. Intrathecal Morphine and Regional Anesthesia After Cesarean Section.
- Conditions
- Interventions
- First Posted Date
- 2023-11-02
- Last Posted Date
- 2024-05-22
- Lead Sponsor
- University of Miami
- Target Recruit Count
- 100
- Registration Number
- NCT06114121
- Locations
- 🇺🇸
University of Miami, Miami, Florida, United States
NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
- Conditions
- Interventions
- First Posted Date
- 2023-10-06
- Last Posted Date
- 2024-04-29
- Target Recruit Count
- 40
- Registration Number
- NCT06070701
- Locations
- 🇷🇴
Cosmin Balan, Bucharest, Sector 2, Romania
Effects of Perioperative Intravenous Dexamethasone in Clinical Outcomes After Total Knee Arthroplasty in a Hispanic Population
- Conditions
- Interventions
- First Posted Date
- 2023-09-18
- Last Posted Date
- 2023-09-18
- Lead Sponsor
- University of Puerto Rico
- Target Recruit Count
- 100
- Registration Number
- NCT06042426
- Locations
- 🇵🇷
University of Puerto Ric-Dr. Federico Trilla Hospital, Carolina, Puerto Rico
PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery
- First Posted Date
- 2023-09-01
- Last Posted Date
- 2023-09-01
- Lead Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
- Target Recruit Count
- 60
- Registration Number
- NCT06021717
- Locations
- 🇲🇾
Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Wilayah Persekutuan, Malaysia
PCA Ketamine-Morphine VS PCA Morphine as Post-Operative Analgesia in Colorectal Surgery.
- First Posted Date
- 2023-08-24
- Last Posted Date
- 2023-08-24
- Lead Sponsor
- National University of Malaysia
- Target Recruit Count
- 60
- Registration Number
- NCT06010056
- Locations
- 🇲🇾
Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Wilayah Persekutuan, Malaysia
Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations
- Conditions
- Interventions
- First Posted Date
- 2023-07-27
- Last Posted Date
- 2024-02-13
- Lead Sponsor
- Istanbul University
- Target Recruit Count
- 112
- Registration Number
- NCT05963139
- Locations
- 🇹🇷
Istanbul University Istanbul Medical Faculty, Istanbul, Turkey
Intravenous Methadone in Perioperative Acute and Chronic Management in Chinese Adult Cardiac Surgical Patients
- Conditions
- Interventions
- First Posted Date
- 2023-06-22
- Last Posted Date
- 2024-02-07
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 86
- Registration Number
- NCT05913284
- Locations
- 🇭🇰
Prince of Wales Hospital, Hong Kong, Hong Kong
Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery
- Conditions
- Interventions
- First Posted Date
- 2023-05-10
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Erasmus Medical Center
- Target Recruit Count
- 208
- Registration Number
- NCT05853263
Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds
- Conditions
- Interventions
- First Posted Date
- 2023-04-06
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- Instituto Nacional de Cancer, Brazil
- Target Recruit Count
- 106
- Registration Number
- NCT05800834
- Locations
- 🇧🇷
National Cancer Institute, Rio De Janeiro, Brazil
Drug Development Updates
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