Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
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The Leukotriene Modifier Or Corticosteroid or Corticosteroid-Salmeterol Trial

First Posted Date
2005-09-12
Last Posted Date
2015-12-09
Lead Sponsor
JHSPH Center for Clinical Trials
Target Recruit Count
500
Registration Number
NCT00156819
Locations
🇺🇸

Washington University, St. Louis, Missouri, United States

🇺🇸

New York Medical College, Valhalla, New York, United States

🇺🇸

University of Miami (and University of South Florida in Tampa), Miami, Florida, United States

and more 16 locations

Pediatric Asthma Study Using Stepwise Treatment With Two Food And Drug Administration Approved Asthma Medications

Phase 3
Completed
Conditions
First Posted Date
2005-09-12
Last Posted Date
2008-10-13
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
200
Registration Number
NCT00158834
Locations
🇳🇱

GSK Investigational Site, Zwolle, Netherlands

Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-07-25
Last Posted Date
2008-01-16
Lead Sponsor
University of Utah
Target Recruit Count
30
Registration Number
NCT00123656
Locations
🇺🇸

University of Utah HSC, Salt Lake City, Utah, United States

Can Advair and Flovent Reduce Systemic Inflammation Related to Chronic Obstructive Pulmonary Disease (COPD)? A Multi-Center Randomized Controlled Trial

First Posted Date
2005-07-19
Last Posted Date
2006-05-09
Lead Sponsor
University of British Columbia
Target Recruit Count
250
Registration Number
NCT00120978
Locations
🇨🇦

Wetaskiwin Lung Laboratory, Wetaskiwin, Alberta, Canada

🇨🇦

Lion's Gate Hospital, North Vancouver, British Columbia, Canada

🇨🇦

University of Alberta Hospital, Edmonton, Alberta, Canada

and more 7 locations

The Addition of Montelukast to Fluticasone in the Treatment of Perennial Allergic Rhinitis

First Posted Date
2005-07-12
Last Posted Date
2014-02-28
Lead Sponsor
University of Chicago
Target Recruit Count
102
Registration Number
NCT00119015
Locations
🇺🇸

The University of Chicago, Chicago, Illinois, United States

A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise

First Posted Date
2005-07-12
Last Posted Date
2019-02-05
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
248
Registration Number
NCT00118716
Locations
🇺🇸

GSK Investigational Site, Milwaukee, Wisconsin, United States

Efficacy and Safety of Omalizumab in Children (6 - < 12 Years) With Moderate-severe, Inadequately Controlled Allergic Asthma

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-03-22
Last Posted Date
2012-04-11
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
628
Registration Number
NCT00079937
Locations
🇺🇸

Clinical Research Institute of Southern Oregon, Medford, Oregon, United States

🇺🇸

Family Allergy and Asthma Center, PC, Atlanta, Georgia, United States

🇺🇸

West Penn Allegheny General Health System, Pittsburgh, Pennsylvania, United States

and more 53 locations
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