Fluticasone propionate

Generic Name
Fluticasone propionate
Brand Names
Advair, Airduo, Airduo Respiclick, Aller-flo, Armonair, Beser, Cutivate, Dymista, Flonase, Flovent, Fluticare, Ticanase, Wixela, Xhance
Drug Type
Small Molecule
Chemical Formula
C25H31F3O5S
CAS Number
80474-14-2
Unique Ingredient Identifier
O2GMZ0LF5W
Background

Fluticasone propionate is a synthetic glucocorticoid. These drugs are available as inhalers, nasal, sprays, and topical treatments for various inflammatory indications. Fluticasone propionate was first approved in 1990.

Indication

Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.

Associated Conditions
Allergic Rhinitis (AR), Allergy to Animal Dander, Allergy to Mold, Allergy to Tree Pollen, Asthma, Bacterial Sinusitis, Chronic Bronchitis, Chronic Obstructive Pulmonary Disease (COPD), Chronic Sinusitis, Dermatitis, Emphysema, Eosinophilic Esophagitis, House Dust Mite Allergy, House dust allergy, Itching of the nose, Nasal Congestion, Non-Allergic Rhinitis, Rhinitis, Rhinitis Perennial, Rhinorrhoea, Seasonal Allergic Rhinitis, Sneezing, Moderate, severe Perennial Allergic Rhinitis (PAR), Moderate, severe Seasonal Allergic Rhinitis
Associated Therapies
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A Study to Evaluate Changes in Nasal Airflow of Loratadine/Pseudoephedrine Tablet and Fluticasone Propionate Nasal Spray in Subjects Following Allergen Exposure

First Posted Date
2018-02-23
Last Posted Date
2019-12-20
Lead Sponsor
Bayer
Target Recruit Count
82
Registration Number
NCT03443843
Locations
🇨🇦

Kingston General Hospital, Kingston, Ontario, Canada

A Study to Assess Efficacy and Safety of Nasacort® Nasal Spray in Comparison With Flixonase® Nasal Spray in Adults Suffering From Perennial Allergic Rhinitis (PAR)

First Posted Date
2017-10-23
Last Posted Date
2022-04-25
Lead Sponsor
Sanofi
Target Recruit Count
260
Registration Number
NCT03317015

Post-marketing Safety Monitoring Program of Fluticasone Propionate (FP) in Chinese Subjects With Asthma Aged 1 to <4 Years

Completed
Conditions
Interventions
First Posted Date
2017-09-06
Last Posted Date
2019-10-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
158
Registration Number
NCT03273946
Locations
🇨🇳

GSK Investigational Site, Shanghai, China

The ENERGITO® 2 Study Compares 2 Inhaled Medicines for Chronic Obstructive Pulmonary Disease (COPD). One Medicine is a Combination of Tiotropium and Olodaterol (Stiolto®) Taken Using the Respimat® Inhaler and the Other Medicine is a Combination of Fluticasone and Salmeterol Taken Using the Diskus

First Posted Date
2017-08-07
Last Posted Date
2020-04-16
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
302
Registration Number
NCT03240575
Locations
🇺🇸

Pulmonary Rsrch Inst of SE MI, Farmington Hills, Michigan, United States

🇺🇸

Spartanburg Medical Research, Spartanburg, South Carolina, United States

🇺🇸

Johns Hopkins Hospital, Baltimore, Maryland, United States

and more 39 locations

Efficacy and Safety Study of GSK3772847 in Subjects With Moderately Severe Asthma

First Posted Date
2017-07-02
Last Posted Date
2020-03-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
165
Registration Number
NCT03207243
Locations
🇺🇦

GSK Investigational Site, Kyiv, Ukraine

Efficacy of Intermittent Tiotropium in Early Childhood Wheezing

First Posted Date
2017-06-27
Last Posted Date
2021-02-16
Lead Sponsor
Helsinki University Central Hospital
Target Recruit Count
80
Registration Number
NCT03199976
Locations
🇫🇮

Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland, Helsinki, Finland

Study of REGN3500 and Dupilumab in Patients With Asthma

First Posted Date
2017-04-13
Last Posted Date
2020-01-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT03112577
Locations
🇺🇸

WCCT Global, Cypress, California, United States

🇬🇧

Celerion, Belfast, United Kingdom

🇬🇧

Hammersmith Medicine Research, London, United Kingdom

and more 2 locations

Cardiovascular Function in COPD Patients

First Posted Date
2017-02-16
Last Posted Date
2019-08-16
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
76
Registration Number
NCT03055988
Locations
🇩🇪

Universitätsklinikum Bonn AöR, Bonn, Germany

🇩🇪

Klinische Forschung Berlin GbR, Berlin, Germany

🇩🇪

Praxis Dr. med. Claus Keller, Frankfurt, Germany

and more 7 locations

The Effect of Inhaled Corticosteroids on Vocal Fold Nodules in Children

First Posted Date
2017-02-02
Last Posted Date
2024-01-09
Lead Sponsor
Joseph Dohar, MD
Target Recruit Count
12
Registration Number
NCT03040596
Locations
🇺🇸

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania, United States

Study of Fluticasone Propionate Multidose Dry Powder Inhaler Compared With Fluticasone Propionate/Salmeterol Multidose Dry Powder Inhaler

First Posted Date
2016-12-02
Last Posted Date
2021-11-09
Lead Sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Target Recruit Count
841
Registration Number
NCT02980133
Locations
🇷🇺

Teva Investigational Site 50440, Tomsk, Russian Federation

🇬🇪

Teva Investigational Site 81044, Tbilisi, Georgia

🇬🇪

Teva Investigational Site 81040, Tbilisi, Georgia

and more 115 locations
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