Dextran
- Generic Name
- Dextran
- Brand Names
- Bion Tears, Colirio Ocusan, Genteal Tears, Genteal Tears Mild, Tears Naturale, Tears Renewed
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- 9004-54-0
- Unique Ingredient Identifier
- -
- Background
Dextran is a polysaccharide that differs from others in that its glucose units are joined together 1:6 glucoside links. The main chain of glucose has short branches at frequent intervals which are probably joined by 1:3 and 1:4 glucoside links. The chains can be composed of about 200,000 glucose units. Many bacteria, like Leuconostoc, can synthesize dextran ...
- Indication
Dextran is used as the restoration of blood mass during surgical interventions if there is hypovolemia due to trauma or dehydration. It is as well used after the presence of hemorrhage in cases of blood loss to a level inferior to 15% of the blood mass, if compatibility test cannot be completed or when blood lots need to be tested for pathogen detection. Dex...
- Associated Conditions
- Blood Circulation Disorder, Capillary disorder, Dry Eyes, Ocular Irritation, Pulmonary Embolism, Pulmonary Embolism caused by procedures associated with a high incidence of thromboembolic complications, Shock, Thrombosis, Venous Thrombosis (Disorder), Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications
- Associated Therapies
- Plasma Volume Replacement, Priming fluid in pump oxygenators therapy
A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Flonase® Allergy Relief in Subjects With Allergic Conjunctivitis
- Conditions
- Interventions
- First Posted Date
- 2022-04-06
- Last Posted Date
- 2022-09-02
- Lead Sponsor
- Andover Research Eye Institute
- Target Recruit Count
- 61
- Registration Number
- NCT05314621
- Locations
- 🇺🇸
Andover Eye Associates, Andover, Massachusetts, United States
A Study Comparing the Efficacy of Pataday® Once Daily Relief Extra Strength to Claritin® Tablets 24-Hour in Subjects With Allergic Conjunctivitis
- Conditions
- Interventions
- First Posted Date
- 2022-03-04
- Last Posted Date
- 2022-05-03
- Lead Sponsor
- Andover Research Eye Institute
- Target Recruit Count
- 58
- Registration Number
- NCT05265910
- Locations
- 🇺🇸
Andover Eye Associates, Andover, Massachusetts, United States
Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit
- Conditions
- Interventions
- First Posted Date
- 2016-08-11
- Last Posted Date
- 2023-05-10
- Lead Sponsor
- Joseph B. Ciolino, MD
- Target Recruit Count
- 76
- Registration Number
- NCT02863809
- Locations
- 🇺🇸
UC Davis Health System Eye Center, Sacramento, California, United States
🇺🇸The Jules Stein Eye Institute, Los Angeles, California, United States
🇺🇸Shiley Eye Institute, University of California, San Diego, San Diego, California, United States
Drug Development Updates
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